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415573

CCc1[nH]c(C(=O)N[C@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2F)nc1Cl
Reaction #72113
title compound
Ausbeute 75.2%DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)c1sc(N2CC[C@H](NC(=O)c3nc(Cl)c(CC)[nH]3)[C@H](F)C2)nc1C
Reaction #72114
title compound
Ausbeute 56.3%DOI: 10.6084/m9.figshare.5104873.v1
CCc1[nH]c(C(=O)N[C@@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2F)nc1Cl
Reaction #72116
title compound
Ausbeute 72.1%DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)c1sc(N2CC[C@@H](NC(=O)c3nc(Cl)c(CC)[nH]3)[C@H](F)C2)nc1C
Reaction #72117
title compound
Ausbeute 82.0%DOI: 10.6084/m9.figshare.5104873.v1
CCc1nn(Cc2cnn([C@@H]3CCN(C(=O)OC(C)(C)C)C[C@H]3F)c2)c2cccc(NC(=O)c3cnc4ccccn34)c12
Reaction #166498
product
DOI: 10.6084/m9.figshare.5104873.v1
CO.ClCCl.[NH4+].[OH-]
Reaction #166499
DCM MeOH NH4OH
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N1CC[C@H](N)[C@H](F)C1
Reaction #168535
tert-butyl (3R,4S)-4-amino-3-fluoro-piperidine-1-carboxylate
DOI: 10.6084/m9.figshare.5104873.v1
CCc1[nH]c(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2F)nc1Cl
Reaction #179627
DOI: 10.1039/C8SC04228D
CC(C)(C)OC(=O)N1CCC(Nc2c(N)cnc3c2ccn3S(=O)(=O)c2ccccc2)C(F)C1
Reaction #192542
DOI: 10.1039/C8SC04228D
CC(C)(C)OC(=O)N1CCC(NC(=O)C2CCC3CN2C(=O)N3O)C(F)C1
Reaction #223337
DOI: 10.1039/C8SC04228D
CC(C)(C)OC(=O)N1CCC(Nc2nc3c(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)cccn3n2)C(F)C1
Reaction #225584
DOI: 10.1039/C8SC04228D
CC(C)(C)OC(=O)N1CCC(N)C(F)(F)C1
Reaction #237527
DOI: 10.1039/C8SC04228D
FC1CNCCC1NCc1ccccc1
Reaction #378611
DOI: 10.1039/C8SC04228D
CC(C)(C)OC(=O)N1CCC(NCc2ccccc2)C(F)C1
Reaction #426885
cis/trans mixture
Ausbeute 80.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N1CC[C@H](N)[C@H](F)C1
Reaction #426886
desired product
Ausbeute 97.4%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N1CC[C@H](NC(=O)OCc2ccccc2)[C@H](F)C1
Reaction #426887
cis-tert-butyl 4-(benzyloxycarbonylamino)-3-fluoropiperidine-1-carboxylate
DOI: 10.6084/m9.figshare.5104873.v1
O=C(N[C@H]1CCNC[C@H]1F)OCc1ccccc1
Reaction #426888
benzyl(cis)-3-fluoropiperidin-4-ylcarbamate
Ausbeute 79.2%DOI: 10.6084/m9.figshare.5104873.v1
F[C@@H]1CNCC[C@@H]1NCc1ccccc1
Reaction #443861
title compound
Ausbeute 94.0%DOI: 10.6084/m9.figshare.5104873.v1
C[C@@H](N[C@@H]1CCNC[C@H]1F)c1ccccc1
Reaction #443862
title compound
Ausbeute 96.0%DOI: 10.6084/m9.figshare.5104873.v1
F[C@@H]1CNCC[C@H]1NCc1ccccc1C(F)(F)F
Reaction #443863
title compound
Ausbeute 97.0%DOI: 10.6084/m9.figshare.5104873.v1
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