部分構造検索

Cc1ccc(N)cc1

CC(=O)Nc1ccc(C(=O)N(CCN2CCC(C(=O)c3ccc(F)cc3)CC2)c2ccc3c(c2)OCO3)cc1

収率 79.0%DOI: 10.6084/m9.figshare.5104873.v1

COc1ccccc1N(CCN1CCC(C(=O)c2ccc(F)cc2)CC1)C(=O)c1ccc(NC(=O)NC(C)(C)C)cc1

収率 77.6%DOI: 10.6084/m9.figshare.5104873.v1

CCOc1cc(N(CC)CC)ccc1C1(c2ccc(N(C)C)cc2N(C)C)OC(=O)c2ccccc21

Reaction #55293

3-(2,4-bis(dimethylamino)phenyl)-3-(2-ethoxy-4-(diethylamino)phenyl)phthalide

DOI: 10.6084/m9.figshare.5104873.v1

O=C(O)Cc1ccc(NC(=O)CCc2cnn(-c3ccccc3)c2-c2ccccc2)cc1

Reaction #58991

(4-{[3-(1,5-diphenyl-1H-pyrazol-4-yl)propanoyl]amino}phenyl)acetic acid

収率 94.0%DOI: 10.6084/m9.figshare.5104873.v1

CC(NC(=O)OC(C)(C)C)c1ccc(N2CC(Oc3ccc(OCC4CC4)cc3)C2)cc1

Reaction #68786

desired product

DOI: 10.6084/m9.figshare.5104873.v1

C[C@H](N)c1ccc(N2CC(Oc3ccc(OCC4CC4)cc3)C2)cc1

Reaction #68787

(S)-1-{4-[3-(4-Cyclopropylmethoxy-phenoxy)-azetidin-1-yl]-phenyl}-ethylamine

DOI: 10.6084/m9.figshare.5104873.v1

C[C@H](NC(=O)OC(C)(C)C)c1ccc(N2CC(Oc3ccc(OCC4CC4)cc3)C2)cc1

Reaction #68797

(S)-(1-{4-[3-(4-Cyclopropylmethoxy-phenoxy)-azetidin-1-yl]-phenyl}-ethyl)-carbamic acid tert-butyl ester

DOI: 10.6084/m9.figshare.5104873.v1

Cc1ccc(NC(=O)NC(=O)c2ccccc2)c(C#N)c1C

Reaction #72663

N-(2-cyano-3,4-dimethylphenylcarbamoyl)benzamide

DOI: 10.6084/m9.figshare.5104873.v1

CC(C(=O)Nc1ccc(C(=O)OC(C)(C)C)cc1)n1cc(Cl)c(-c2cc(Cl)ccc2C(F)F)cc1=O

Reaction #84986

tert-Butyl 4-[(2-{5-chloro-4-[5-chloro-2-(difluoromethyl)phenyl]-2-oxopyridin-1(2H)-yl}propanoyl)amino]benzoate

DOI: 10.6084/m9.figshare.5104873.v1

CC(C)CC(C(=O)Nc1ccc(C(=O)OC(C)(C)C)cc1)n1cc(Cl)c(-c2cc(Cl)ccc2C#N)cc1=O

Reaction #85189

tert-Butyl 4-({2-[5-chloro-4-(5-chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]-4-methylpentanoyl}amino)benzoate

DOI: 10.6084/m9.figshare.5104873.v1

CC(C(=O)Nc1ccc(C(=O)O)cc1)n1cc(Cl)c(-c2cc(Cl)ccc2C(F)F)cc1=O

Reaction #85256

4-[(2-{5-Chloro-4-[5-chloro-2-(difluoromethyl)phenyl]-2-oxopyridin-1(2H)-yl}propanoyl)amino]benzoic acid

DOI: 10.6084/m9.figshare.5104873.v1

CC(C)CC(C(=O)Nc1ccc(C(=O)O)cc1)n1cc(Cl)c(-c2cc(Cl)ccc2C#N)cc1=O

Reaction #85337

4-({2-[5-Chloro-4-(5-chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]-4-methylpentanoyl}amino)benzoic acid

DOI: 10.6084/m9.figshare.5104873.v1

COc1cc(-n2nc(-c3c(C)cccc3Cl)[nH]c2=O)ccc1C(=O)Nc1ccc(F)c(C(F)F)c1

Reaction #87746

desired product

収率 18.6%DOI: 10.6084/m9.figshare.5104873.v1

COc1cc(-n2nc(-c3c(C)cccc3Cl)[nH]c2=O)ccc1C(=O)Nc1cccc(C(F)F)c1

Reaction #87747

desired product

収率 26.9%DOI: 10.6084/m9.figshare.5104873.v1

COc1cc(-n2nc(-c3c(C)cccc3Cl)[nH]c2=O)ccc1C(=O)Nc1cccc(C(F)(F)F)c1

Reaction #87749

desired product

収率 22.3%DOI: 10.6084/m9.figshare.5104873.v1

COc1cc2c(cc1N1CCOCC1)CCC2=O

Reaction #90512

crude compound 13

DOI: 10.6084/m9.figshare.5104873.v1

$COc1cc2c(cc1N1CCOCC1)C/C(=C\C1CCN(Cc3ccccc3)CC1)C2=O$

Reaction #90514

(E)-2-((1-benzylpiperidin-4-yl)methylene)-6-methoxy-5-morpholino-2, 3-dihydro-1H-inden-1-one

DOI: 10.6084/m9.figshare.5104873.v1

$COc1cc2c(cc1N1CCOCC1)C/C(=C\c1cc(Br)cc(OC(F)(F)F)c1)C2=O$

Reaction #90517

(E)-2-(3-bromo-5-(trifluoromethoxy)benzylidene)-6-methoxy-5-morpholino-2, 3-dihydro-1H-inden-1-one

DOI: 10.6084/m9.figshare.5104873.v1

$COc1cc2c(cc1N1CCOCC1)C/C(=C\c1c(F)ccc(Br)c1F)C2=O$

Reaction #90519

crude compound 41

DOI: 10.6084/m9.figshare.5104873.v1

$COc1cc2c(cc1N1CCOCC1)C/C(=C\c1cc(Cl)ccc1C(F)(F)F)C2=O$

Reaction #90521

crude compound 52

DOI: 10.6084/m9.figshare.5104873.v1

1 ページ次のページ