反応 #72663

反応方程式

6-amino-2,3-dimethylbenzonitrile

benzoyl isocyanate

→

N-(2-cyano-3,4-dimethylphenylcarbamoyl)benzamide

反応条件

実験手順

Prepared as in Example 53a from 6-amino-2,3-dimethylbenzonitrile and benzoyl isocyanate as a off-white solid (210 mg, 72%). 1H NMR (400 MHz, DMSO-d6) δ2.27 (s, 3H), 2.43 (s, 3H), 7.48 (d, J=6.4 Hz, 2H), 7.53 (t, J=8 Hz, 7.6 Hz, 2H), 7.65 (t, J=7.2 Hz, 1H), 7.94 (d, J=8 Hz, 1H), 8.03 (d, J=7.6 Hz, 2H), 11.29 (s, 1H), 11.37 (s, 1H). MS 293 (MH+).

出典