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533795

COc1cc(N(CC(C)C)c2cc(C(F)(F)F)ccc2F)cnc1C(=O)[C@H]1C[C@@H]1C(=O)O
Reaction #683
Ausbeute 15.7%
COc1cc(N(CC(C)C)c2cc(C(F)(F)F)ccc2F)cnc1C(=O)[C@H]1C[C@@H]1C(=O)O
Reaction #684
Ausbeute 29.1%
CCOC(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)c(-c2ccccc2)n1
Reaction #40798
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)c1ccc(-c2ccccc2)c(-c2ccc(C(F)(F)F)cc2)n1
Reaction #40802
title compound
DOI: 10.6084/m9.figshare.5104873.v1
Cn1c(Nc2cc(C(F)(F)F)ccc2F)nc2cc(OC3(C(=O)O)C=CC=CN3)ccc21
Reaction #41740
2-{[2-fluoro-5-(trifluoromethyl)phenylamino)-1-methylbenzimidazol-5-yloxy)pyridine-2-carboxylic acid
DOI: 10.6084/m9.figshare.5104873.v1
Cn1c(Nc2cc(C(F)(F)F)ccc2F)nc2cc(OC3(C4CCN(CCNC=O)C4)C=CC=CN3)ccc21
Reaction #41741
4-(2-{[2-fluoro-5-(trifluoromethyl)phenyl]amino-1-methylbenzimidazol-5-yloxy)-(2-pyridyl)]-N-(2-pyrrolidinylethyl)carboxamide
DOI: 10.6084/m9.figshare.5104873.v1
O=C(O)C1CCN(Cc2cc(Oc3ccc4c(ccn4C(=O)Nc4ccc(F)c(C(F)(F)F)c4)c3)ncn2)CC1
Reaction #73392
title compound
DOI: 10.6084/m9.figshare.5104873.v1
O=C(NCc1ccc(Cl)c(-n2nc(-c3ccc(C#CC4CC4)cc3)[nH]c2=O)c1)C(F)(F)F
Reaction #87851
desired product
Ausbeute 7.6%DOI: 10.6084/m9.figshare.5104873.v1
CC(SC1COC(C=Cc2ccc(C(F)(F)F)cc2)OC1)C(O)(Cn1cncn1)c1ccc(F)cc1F
Reaction #178281
DOI: 10.1039/C8SC04228D
CN1CCC(c2c[nH]c3ccc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)nc23)CC1
Reaction #181530
DOI: 10.1039/C8SC04228D
Cc1c(Br)c(C(F)(F)F)nn1CC(=O)N1CCN(c2ccc(Cl)cc2)CC1
Reaction #187328
DOI: 10.1039/C8SC04228D
O=C(O)C1CCN(Cc2cc(Oc3ccc4c(ccn4C(=O)Nc4ccc(F)c(C(F)(F)F)c4)c3)ncn2)CC1
Reaction #187616
DOI: 10.1039/C8SC04228D
O=C(Nc1ccc(CC2CCN(S(=O)(=O)N3CCCCC3)CC2)cc1)C(F)(F)F
Reaction #187725
DOI: 10.1039/C8SC04228D
O=C(NCC1CC1)Nc1ccc(C(=O)N2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2C(=O)O)cc1
Reaction #187769
DOI: 10.1039/C8SC04228D
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3-c3ccc(C(F)(F)F)cc3)CC2)ccc1Cl
Reaction #194841
DOI: 10.1039/C8SC04228D
CCN(Cc1nc(-c2cccc(C(=O)O)c2)oc1C)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1
Reaction #201112
DOI: 10.1039/C8SC04228D
COc1ccc(N(CCc2ccc(C(F)(F)F)cc2)C(=O)C(C(=O)O)c2ccccc2)cc1OC
Reaction #206621
DOI: 10.1039/C8SC04228D
N#Cc1cc(C(=O)C=C(c2cc(Cl)cc(Cl)c2)C(F)(F)F)ccc1-n1cncn1
Reaction #223197
DOI: 10.1039/C8SC04228D
O=C(Nc1ccccc1)Nc1ccc(C(=O)N2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)cc1F
Reaction #226617
DOI: 10.1039/C8SC04228D
CC1CCN(c2ncc(C(=O)NCc3ccc4[nH]c(C(F)(F)F)cc4c3)cn2)CC1
Reaction #226863
DOI: 10.1039/C8SC04228D
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