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441182

CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](c2cccc(F)c2F)CNC1=S
Reaction #42666
title compound
Выход 188.0%DOI: 10.6084/m9.figshare.5104873.v1
N[C@@H]1CC[C@@H](c2cccc(F)c2F)CNC1=O
Reaction #48410
(3R,6S)-3-Amino-6-(2,3-difluorophenyl)azepan-2-one
DOI: 10.6084/m9.figshare.5104873.v1
CSCCN1C[C@H](c2cccc(F)c2F)CC[C@@H](NC(=O)OC(C)(C)C)C1=O
Reaction #48414
title compound
Выход 37.2%DOI: 10.6084/m9.figshare.5104873.v1
CSCCN1C[C@H](c2cccc(F)c2F)CC[C@@H](N)C1=O
Reaction #48415
(3R,6S)-3-Amino-6-(2,3-difluorophenyl)-1-[2-(methylthio)ethyl]azepan-2-one
DOI: 10.6084/m9.figshare.5104873.v1
CS(=O)CCN1C[C@H](c2cccc(F)c2F)CC[C@@H](NC(=O)OC(C)(C)C)C1=O
Reaction #48416
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CS(=O)CCN1C[C@H](c2cccc(F)c2F)CC[C@@H](N)C1=O
Reaction #48417
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](c2cccc(F)c2F)CN(CCS(C)(=O)=O)C1=O
Reaction #48418
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CS(=O)(=O)CCN1C[C@H](c2cccc(F)c2F)CC[C@@H](N)C1=O
Reaction #48419
title compound
DOI: 10.6084/m9.figshare.5104873.v1
COCCN1C[C@H](c2cccc(F)c2F)CC[C@@H](NC(=O)OC(C)(C)C)C1=O
Reaction #48420
title compound
DOI: 10.6084/m9.figshare.5104873.v1
COCCN1C[C@H](c2cccc(F)c2F)CC[C@@H](N)C1=O
Reaction #48421
(3R,6S)-3-Amino-6-(2,3-difluorophenyl)-1-(2-methoxyethyl)azepan-2-one
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](c2cccc(F)c2F)CN(CC(F)(F)F)C1=O
Reaction #48422
title compound
Выход 82.0%DOI: 10.6084/m9.figshare.5104873.v1
N[C@@H]1CC[C@@H](c2cccc(F)c2F)CN(CC(F)(F)F)C1=O
Reaction #48423
(3R,6S)-3-Amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](c2cccc(F)c2F)CN(Cc2ccccn2)C1=O
Reaction #48424
title compound
Выход 99.6%DOI: 10.6084/m9.figshare.5104873.v1
N[C@@H]1CC[C@@H](c2cccc(F)c2F)CN(Cc2ccccn2)C1=O
Reaction #48425
(3R,6S)-3-Amino-6-(2,3-difluorophenyl)-1-(pyridin-2-ylmethyl)azepan-2-on
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](c2cccc(F)c2F)CN(c2ccncc2)C1=O
Reaction #48426
title compound
Выход 22.4%DOI: 10.6084/m9.figshare.5104873.v1
N[C@@H]1CC[C@@H](c2cccc(F)c2F)CN(c2ccncc2)C1=O
Reaction #48427
(3R,6S)-3-Amino-6-(2,3-difluorophenyl)-1-pyridin-4-ylazepan-2-one
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(O)CN1C[C@H](c2cccc(F)c2F)CC[C@@H](N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C1=O
Reaction #48428
title compound
Выход 33.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(O)CN1C[C@H](c2cccc(F)c2F)CC[C@@H](N)C1=O
Reaction #48429
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)[C@@H]1CC[C@@H](c2cccc(F)c2F)CN(Cc2nccs2)C1=O
Reaction #48430
title compound
Выход 56.3%DOI: 10.6084/m9.figshare.5104873.v1
N[C@@H]1CC[C@@H](c2cccc(F)c2F)CN(Cc2nccs2)C1=O
Reaction #48431
title compound
Выход 0.1%DOI: 10.6084/m9.figshare.5104873.v1
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