1-(3-dimethylaminopropyl)-3-ethylcarbodiimide

CC(C)(C)OC(=O)NCC(=O)N[C@@H](CC(=O)OC1CCCCC1)C(=O)O.Cc1ccc(CO[C@H]2[C@H](O)[C@H](O)C(O)O[C@@H]2CO)cc1
Reaction #1813
titled compound
수율 89.2%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-1998_03
CNC(=O)c1cc(N)c(F)cc1F
Reaction #6961
5-amino-2,4-difluoro-N-methylbenzamide
수율 41.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
O=C(NC1CC1)c1ccc(F)c(O)c1
Reaction #6966
3-hydroxy-4-fluoro-N-cyclopropylbenzamide
수율 61.5%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CC(=O)NC(Cc1ccc(O)cc1)C(=O)NC(Cc1ccc(F)cc1)C(=O)N1CC(=O)N(CCc2ccc3ccccc3c2)CC1CCC#N
Reaction #8622
crude product
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CNC(=O)C(Cc1ccc2ccccc2c1)N1CCN(C(=O)C(Cc2ccc(F)cc2)NC(=O)C(Cc2ccccc2O)NC(C)=O)C(CCOC(C)=O)C1
Reaction #8629
acetic acid 2-[1-{2-[2-acetylamino-3-(hydroxyphenyl)propionyl-amino]-3-(4-fluorophenyl)propionyl}-4-(1-methylcarbamoyl-2-naphthalen-2-ylethyl)-piperazin-2-yl]ethyl ester
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C[Si](C)(C)CCOC(=O)[C@@H]1CCCC[C@H]1C(=O)c1ccc(Br)cc1
Reaction #9636
trans-(trimethylsilyl)ethyl 2-(4-bromobenzoyl)cyclohexanecarboxylate
수율 37.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
O=C(CC(F)(F)F)N[C@@]12C[C@H]1COC2=O
Reaction #10170
3,3,3-trifluoro-N-[(±)-trans-2-oxo-3-oxabicyclo[3.1.0]hex-1-yl]-propanamide
수율 45.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CC(C)(C)OC(=O)NNC(=O)c1cc(F)c(F)cc1NC1CC1
Reaction #10399
N2-(2-cyclopropylamino-4,5-difluorobenzoyl)hydrazinecarboxylic acid tert-butyl ester
수율 81.4%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CC(C)(C)OC(=O)N(N)C(=O)c1cc(F)c(F)cc1Nc1ccc(F)cc1F
Reaction #10400
[2-(2,4-difluoroanilino)-4,5-difluorobenzoyl]-hydrazinecarboxylic acid tert-butyl ester
수율 72.5%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CC(C)(C)OC(=O)N(N)C(=O)c1cc(F)c(F)c(Cl)c1NC1CC1
Reaction #10401
title compound
수율 63.1%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
Cc1c(Cl)cccc1S(=O)(=O)Nc1ncc(CC(=O)N2CCOCC2)s1
Reaction #10466
desired product
수율 10.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
Cc1c(Cl)cccc1S(=O)(=O)Nc1ncc(CC(=O)N(C(C)C)C(C)C)s1
Reaction #10467
desired product
수율 9.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
COC(=O)c1ccc(C(=O)/C=C/c2cc(-c3cc4ccccc4s3)c(OC)cc2OC)cc1
Reaction #10842
title compound
수율 34.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C=CCN(C(=O)OCc1ccccc1)c1cnc2n(c1=O)[C@H](C(=O)Nc1ccccc1)CC2
Reaction #11064
18b
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C=CCN(C(=O)OCc1ccccc1)c1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OCc3ccccc3)cc1)C[C@@]2(C)N=[N+]=[N-]
Reaction #11067
intermediate
수율 90.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CC(C)(C)OC(=O)NC(=N)c1ccc(CNC(=O)[C@@H]2CCc3ncc(N(Cc4cccc(C(F)(F)F)c4)C(=O)OCc4ccccc4)c(=O)n32)cc1
Reaction #11083
intermediate 25b
수율 79.2%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C=CC[C@@H]1C[C@@H](C(=O)NCc2ccc(C(=N)NC(=O)OCc3ccccc3)cc2)n2c1ncc(N(CC=C)C(=O)OCc1ccccc1)c2=O
Reaction #11087
intermediate 28e
수율 20.8%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CC(=O)NS(=O)(=O)Cc1cc(Cl)ccc1OCC(=O)N1C[C@H](C)N(Cc2ccc(F)cc2)C[C@H]1C
Reaction #11767
title compound
수율 74.1%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
—
Reaction #40357
intermediate 1-3
수율 88.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
COc1c(Cl)cc2c([nH]c3cnccc32)c1NC(=O)c1cccnc1C
Reaction #40458
desired product
수율 50.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
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