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199177

CON=C(C(=O)N[C@@H]1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=CCS[C@H]12)c1nc(NC(=O)OCc2ccccc2)sc1F
Reaction #214080
7β-[2-(2-carbobenzoxyamino-5-fluoro-4-thiazolyl)-2-methoxyiminoacetamido]-3-cephem-4-carboxylic acid diphenylmethyl ester
수율 70.9%DOI: 10.6084/m9.figshare.5104873.v1
CON=C(C(=O)N[C@@H]1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=CCS[C@H]12)c1nc(NC(=O)OCc2ccccc2)sc1F
Reaction #214084
7β-[2-(2-carbobenzoxyamino-5-fluoro-4-thiazolyl)-2-methoxyiminoacetamido]-3-cephem-4-carboxylic acid diphenylmethyl ester
DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #305259
desired acid
DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1ccc(-c2nc(N3CCN(C)CC3)sc2F)cc1
Reaction #305268
title compound
수율 74.0%DOI: 10.6084/m9.figshare.5104873.v1
COC1(OC)COC2C(Cl)CN(C(=O)C(CNC(=O)c3ccc(-c4nc(N5CCN(C)CC5)sc4F)cc3)C(C)C)C21
Reaction #305274
title compound
수율 85.0%DOI: 10.6084/m9.figshare.5104873.v1
Cc1cc(-c2cc(F)cc(F)c2)cc(C(=O)Nc2nc(C)c(F)s2)n1
Reaction #395831
DOI: 10.1039/C8SC04228D
CCOC(=O)C(C)(C)c1nc(N(Cc2ccc(OC)cc2)C(=O)OC(C)(C)C)sc1F
Reaction #611588
compound
수율 24.0%DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)C(C)(C)c1nc(N)sc1F
Reaction #611589
2-(2-Amino-5-fluoro-thiazol-4-yl)-2-methyl-propionic acid ethyl ester
수율 97.8%DOI: 10.6084/m9.figshare.5104873.v1
Cc1cc(-c2cc(F)cc(F)c2)cc(C(=O)Nc2nc(C)c(F)s2)n1
Reaction #639729
title compound
DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)/C(=N\O)c1nc(N)sc1F
Reaction #706409
methyl 2-(2-amino-5-fluorothiazol-4-yl)-2-(Z)-(hydroxyimino)acetate
수율 25.1%DOI: 10.6084/m9.figshare.5104873.v1
Nc1nc(/C(=N/O)C(=O)O)c(F)s1
Reaction #706410
2-(2-amino-5-fluorothiazol-4-yl)-2-(Z)-(hydroxyimino)acetic acid
수율 35.3%DOI: 10.6084/m9.figshare.5104873.v1
O=CNc1nc(/C(=N/OC=O)C(=O)O)c(F)s1
Reaction #706411
2-(5-fluoro-2-formylaminothiazol-4-yl)-2-(Z)-(formyloxyimino)acetic acid
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc(SCc2nc(NC(=O)NCc3cccc(F)c3)sc2F)cc1
Reaction #771497
DOI: 10.1039/C8SC04228D
COC1(OC)COC2C(Cl)CN(C(=O)C(CNC(=O)c3ccc(-c4nc(N5CCN(C)CC5)sc4F)cc3)C(C)C)C21
Reaction #915040
DOI: 10.1039/C8SC04228D
COc1ccc(SCc2nc(NC(=O)OC(C)(C)C)sc2F)cc1
Reaction #925843
DOI: 10.1039/C8SC04228D
CN1CCN(c2nc(-c3ccc(C(=O)O)cc3)c(F)s2)CC1
Reaction #971573
4-[5-fluoro-2-(4-methyl-piperazin-1-yl)-thiazol-4-yl]-benzoic acid
DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1ccc(-c2nc(N3CCN(C)CC3)sc2F)cc1
Reaction #971582
title compound
수율 74.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)Nc1nc(CO)c(F)s1
Reaction #1023090
DOI: 10.1039/C8SC04228D
CN1CCN(c2nc(-c3ccc(C(=O)O)cc3)c(F)s2)CC1
Reaction #1114800
4-[5-fluoro-2-(4-methyl-piperazin-1-yl)-thiazol-4-yl]-benzoic acid
DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1ccc(-c2nc(N3CCN(C)CC3)sc2F)cc1
Reaction #1114808
title compound
수율 74.0%DOI: 10.6084/m9.figshare.5104873.v1
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