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242580

CCc1nc(-c2ccccc2)cn1Cc1ccc2c(c1)COc1ccccc1C2=C(C)C#N

Reaction #235916

DOI: 10.1039/C8SC04228D

CCc1nc2c(C)cc(C)nc2[nH]1

Reaction #255091

DOI: 10.1039/C8SC04228D

CCc1nc2ccccc2n1Cc1ccc2c(c1)COc1ccccc1C2=C(C)C#N

Reaction #297232

DOI: 10.1039/C8SC04228D

CCc1nc2c(C)cc(C)nc2[nH]1

Reaction #407780

DOI: 10.1039/C8SC04228D

$CCc1nc(-c2ccccc2)cn1Cc1ccc2c(c1)COc1ccccc1/C2=C(\C)C#N$

Reaction #539320

(E)-2-[8-(2-ethyl-4-phenylimidazol-1-yl)methyl-6,11-dihydrodibenzo[b,e]oxepin-11-ylidene]propiononitrile

Yield 99.6%DOI: 10.6084/m9.figshare.5104873.v1

C/C(C#N)=C1/c2ccc(Cn3ncc4ccccc43)cc2COc2ccccc21

Reaction #539321

(E)-2-[8-(indazol-1-yl)methyl-6,11-dihydrodibenzo[b,e]oxepin-11-ylidene]propiononitrile

Yield 64.0%DOI: 10.6084/m9.figshare.5104873.v1

$CCc1nc2ccccc2n1Cc1ccc2c(c1)COc1ccccc1/C2=C(\C)C#N$

Reaction #539322

(E)-2-[8-(2-ethylbenzimidazol-1-yl)methyl-6,11-dihydrodibenzo[b,e]oxepin-11-ylidene]propiononitrile

Yield 77.6%DOI: 10.6084/m9.figshare.5104873.v1

$CCCc1nc2c(C(=O)N3CCC(O)CC3)cccc2n1Cc1ccc2c(c1)COc1ccccc1/C2=C(\C)C#N$

Reaction #539342

(E)-2-{8-[4-(4-hydroxy-1-piperidinecarbonyl)-2-propylbenzimidazol-1-yl]methyl-6,11-dihydrodibenzo[b,e]oxepin-11-ylidene}propiononitrile

Yield 100.0%DOI: 10.6084/m9.figshare.5104873.v1

$CCCc1nc2c(C(=O)NCCO)cccc2n1Cc1ccc2c(c1)COc1ccccc1/C2=C(\C)C#N$

Reaction #539343

(E)-N-(2-hydroxyethyl) 1-[11-(1-cyanoethylidene)-6,11-dihydrodibenzo[b,e]oxepin-8-yl]methyl-2-propylbenzimidazole-4-carboxamide

Yield 99.1%DOI: 10.6084/m9.figshare.5104873.v1

CCCc1nc2c(C(=O)NCCO)cccc2n1Cc1ccc2c(c1)COc1ccccc1C2=C(C)C#N

Reaction #906657

DOI: 10.1039/C8SC04228D

$COCc1nc2ccccc2n1Cc1ccc2c(c1)COc1cc(F)ccc1/C2=C(\C)C#N$

Reaction #956686

Yield 87.0%DOI: 10.6084/m9.figshare.5104873.v1

C/C(C#N)=C1/c2ccc(Cn3c(C(C)C)nc4ccccc43)cc2COc2cc(F)ccc21

Reaction #956687

Yield 98.0%DOI: 10.6084/m9.figshare.5104873.v1

C/C(C#N)=C1/c2ccc(Cn3c(C4CC4)nc4ccccc43)cc2COc2cc(F)ccc21

Reaction #956688

Yield 96.3%DOI: 10.6084/m9.figshare.5104873.v1

C/C(C#N)=C1/c2ccc(Cn3c(C4CCC4)nc4ccccc43)cc2COc2cc(F)ccc21

Reaction #956689

Yield 90.3%DOI: 10.6084/m9.figshare.5104873.v1

C/C(C#N)=C1/c2ccc(Cn3c(C4CCCC4)nc4ccccc43)cc2COc2cc(F)ccc21

Reaction #956690

Yield 95.3%DOI: 10.6084/m9.figshare.5104873.v1

C/C(C#N)=C1/c2ccc(Cn3c(CC4CC4)nc4ccccc43)cc2COc2cc(F)ccc21

Reaction #956691

Yield 93.0%DOI: 10.6084/m9.figshare.5104873.v1

$CCc1nc2ccccc2n1Cc1ccc2c(c1)COc1cc(F)ccc1/C2=C(\C)C#N$

Reaction #956692

Yield 96.0%DOI: 10.6084/m9.figshare.5104873.v1

C/C(C#N)=C1/c2ccc(Cn3c(C(F)(F)F)nc4ccccc43)cc2COc2cc(F)ccc21

Reaction #956693

Yield 88.9%DOI: 10.6084/m9.figshare.5104873.v1

C/C(C#N)=C1/c2ccc(Cn3c(C4CC(F)(F)C4)nc4ccccc43)cc2COc2cc(F)ccc21

Reaction #956696

Yield 96.9%DOI: 10.6084/m9.figshare.5104873.v1

C/C(C#N)=C1/c2ccc(Cn3c(C4(C)CC4)nc4ccccc43)cc2COc2cc(F)ccc21

Reaction #956697

Yield 40.0%DOI: 10.6084/m9.figshare.5104873.v1

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