Reaction #956693

Reaction equation

2-(trifluoromethyl)-1H-benzo[d]imidazole

(E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile

→

title compound

Yield 88.9%

(E)-2-(3-fluoro-8-{[2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl]methyl}dibenzo[b,e]oxepin-11(6H)-ylidene)propanenitrile

Yield 88.9%

Conditions

Workup

1. 1
   Otherobtained in Reference Example 1

Procedure

Using 2-(trifluoromethyl)-1H-benzo[d]imidazole (62 mg, 0.335 mmol) and (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile (120 mg, 0.335 mmol) obtained in Reference Example 1, and in the same manner as in Reference Example 1A, the title compound (138 mg, 88%) was obtained.

Source