4-tert-butylbenzen-1,2-diamine

COc1ccc(CNc2ncnc3c2ccn3C2CC(CN(C)C3CC(CCC(=O)Nc4ccc(C(C)(C)C)cc4N)C3)C3OC(C)(C)OC32)c(OC)c1
Reaction #259139
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
COc1ccc(CNc2ncnc3c2ccn3[C@@H]2O[C@H](CN(C)C3CC(CC(=O)Nc4ccc(C(C)(C)C)cc4N)C3)[C@H]3OC(C)(C)O[C@H]32)c(OC)c1
Reaction #598775
title compound
Ausbeute 82.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2015_08
COc1ccc(CNc2ncnc3c2ccn3[C@@H]2C[C@H](CN(C)C3CC(CCC(=O)Nc4ccc(C(C)(C)C)cc4N)C3)[C@H]3OC(C)(C)O[C@H]32)c(OC)c1
Reaction #598796
solid
Ausbeute 42.1%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2015_08
COc1ccc(CNc2ncnc3c2ccn3[C@@H]2C[C@H](CN(C(C)C)C3CC(CCc4nc5cc(C(C)(C)C)ccc5[nH]4)C3)[C@H]3OC(C)(C)O[C@H]32)c(OC)c1
Reaction #598806
desired intermediate
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2015_08
CCN(C[C@H]1C[C@@H](n2ccc3c(NCc4ccc(OC)cc4OC)ncnc32)[C@@H]2OC(C)(C)O[C@H]12)C1CC(CCC(=O)Nc2ccc(C(C)(C)C)cc2N)C1
Reaction #598819
desired compound
Ausbeute 77.8%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2015_08
COc1ccc(CNc2ncnc3c2ccn3[C@@H]2C[C@H](CN(CC(C)C)C3CC(CCC(=O)Nc4ccc(C(C)(C)C)cc4N)C3)[C@H]3OC(C)(C)O[C@H]32)c(OC)c1
Reaction #598838
amide
Ausbeute 81.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2015_08
COc1ccc(CNc2ncnc3c2ncn3[C@@H]2C[C@H](CN(C(C)C)C3CC(CCC(=O)Nc4ccc(C(C)(C)C)cc4N)C3)[C@@H](O)[C@H]2O)c(OC)c1
Reaction #598841
amide
Ausbeute 91.9%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2015_08
CCN(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21)C1CC(CCC(=O)Nc2ccc(C(C)(C)C)cc2N)C1
Reaction #598873
N-(2-amino-4-(tert-butyl)phenyl)-3-(3-((((3aR,4R,6R,6aR)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl)(ethyl)amino)cyclobutyl)propanamide
Ausbeute 61.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2015_08
COc1ccc(CNc2ncnc3c2ccn3[C@@H]2O[C@H](CN(C(C)C)C3CC(CCC(=O)Nc4ccc(C(C)(C)C)cc4N)C3)[C@H]3OC(C)(C)O[C@H]32)c(OC)c1
Reaction #598876
desired compound
Ausbeute 50.2%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2015_08
CC(C)(C)c1ccc(NC(=O)c2nccc(Cl)c2CO[Si](C)(C)C(C)(C)C)c(N)c1
Reaction #607507
N-(2-amino-4-(tert-butyl)phenyl)-3-(((tert-butyldimethylsilyl)oxy)methyl)-4-chloropicolinamide
Ausbeute 67.6%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_05
COc1ccc(Nc2nc3ccc(C(C)(C)C)cc3[nH]2)c(Oc2ccccc2C(C)(C)C)n1
Reaction #642577
(6-tert-Butyl-1H-benzoimidazol-2-yl)-[2-(2-tert-butyl-phenoxy)-6-methoxy-pyridin-3-yl]-amine
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2011_11
CC(C)(C)c1ccc2nc(Nc3cccnc3Oc3cccc(C(F)(F)F)c3)[nH]c2c1
Reaction #642580
(6-tert-Butyl-1H-benzoimidazol-2-yl)-[2-(3-trifluoromethyl-phenoxy)-pyridin-3-yl]-amine
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2011_11
CC(C)(C)c1ccc2nc(O)cnc2c1
Reaction #685705
title compound
Ausbeute 10.4%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2011_03
CN1CCCN(CCCOc2ccc(-c3nc4cc(C(C)(C)C)ccc4[nH]3)cc2Cl)CC1
Reaction #734140
title compound
Ausbeute 34.1%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_04
CN1CCN(CCCCOc2cccc(-c3nc4cc(C(C)(C)C)ccc4[nH]3)c2)CC1
Reaction #734142
title compound
Ausbeute 93.9%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_04
Cc1cc(-c2nc3cc(C(C)(C)C)ccc3[nH]2)ccc1OCCCN1CCN(C)CC1
Reaction #734148
title compound
Ausbeute 81.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_04
CN1CCCN(CCCOc2ccc(-c3nc4cc(C(C)(C)C)ccc4[nH]3)cc2Cl)CC1
Reaction #734170
title compound
Ausbeute 34.1%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_04
CN1CCN(CCCCOc2cccc(-c3nc4cc(C(C)(C)C)ccc4[nH]3)c2)CC1
Reaction #734172
title compound
Ausbeute 93.9%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_04
Cc1cc(-c2nc3cc(C(C)(C)C)ccc3[nH]2)ccc1OCCCN1CCN(C)CC1
Reaction #734178
title compound
Ausbeute 81.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_04
CC(C)(C)c1ccc2[nH]c(-c3ccc(N)cc3)nc2c1
Reaction #999609
title compound
Ausbeute 98.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2011_09
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