tert-butyl (2R)-2-methylpiperazine-1-carboxylate

COc1cc(N2CCN[C@H](C)C2)ccc1OCc1ccccc1
Reaction #305
Ausbeute 40.3%750 AstraZeneca ELN dataset
CCOc1ccc(N2CCN[C@H](C)C2)cc1OC
Reaction #749
Ausbeute 50.8%750 AstraZeneca ELN dataset
C[C@@H]1CN(c2ccc(S(C)(=O)=O)cc2)CCN1C(=O)OC(C)(C)C
Reaction #787
Ausbeute 0.0%750 AstraZeneca ELN dataset
C[C@@H]1CN(Cc2cccc(-c3ccnc(Cl)n3)c2)CCN1C(=O)OC(C)(C)C
Reaction #43204
oily product
Ausbeute 53.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
C[C@@H]1CN(S(=O)(=O)c2ccc(C(F)(F)F)cc2)CCN1
Reaction #69579
title compound
Ausbeute 82.8%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_09
C[C@@H]1CN(S(=O)(=O)c2ccc(Cl)cc2)CCN1
Reaction #69580
title compound
Ausbeute 78.7%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_09
C[C@@H]1CN(S(=O)(=O)c2ccc(C(F)(F)F)cc2)CCN1
Reaction #71650
title compound
Ausbeute 82.8%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_09
C[C@@H]1CN(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)CCN1
Reaction #71656
title compound
Ausbeute 90.1%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_09
C[C@@H]1CN(c2ccc(Cl)nn2)CCN1C(=O)OC(C)(C)C
Reaction #166290
compound 11
Ausbeute 82.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
CC(=O)N1CCN(C(=O)OC(C)(C)C)[C@H](C)C1
Reaction #167936
(R)-tert-butyl 4-acetyl-2-methylpiperazine-1-carboxylate
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
C[C@@H]1CN(S(=O)(=O)c2ccc(C(F)(F)F)cc2)CCN1
Reaction #505460
title compound
Ausbeute 83.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2012_01
C[C@@H]1CN(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)CCN1
Reaction #505464
(3R)-3-methyl-1-({4-[(trifluoromethyl)oxy]phenyl}sulfonyl)piperazine
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2012_01
COC(=O)c1cnc(N2CCN(C(=O)OC(C)(C)C)C[C@H]2C)cn1
Reaction #534264
(R)-2-Methyl-4-boc-3,4,5,6-tetrahydro-2H-[1,2′]bipyrazinyl-5′-carboxylic acid methyl ester
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_07
CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2ccc(F)c(-c3cccc(CN4CCN[C@H](C)C4)c3)c2)c1
Reaction #651812
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2011_11
CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)CC(=O)NCc1cccc(-c2cccc(CN3CCN[C@H](C)C3)c2)c1
Reaction #744611
title compound
Ausbeute 9.9%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2011_12
C[C@@H]1CN(C2CN(C(c3ccccc3)c3ccccc3)C2)CCN1C(=O)OC(C)(C)C
Reaction #794698
title compound
Ausbeute 90.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2015_11
C[C@@H]1CN(c2ccc(Cl)nn2)CCN1C(=O)OC(C)(C)C
Reaction #963122
solid
Ausbeute 82.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2015_03
CC(C)N1CCN(C(=O)OC(C)(C)C)[C@H](C)C1
Reaction #966782
(R)-1-Boc-2-methyl-4-isopropylpiperazine
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2015_03
CC(C)N1CCN(C(=O)OC(C)(C)C)[C@@H](C)C1
Reaction #966785
(S)-1-Boc-2-methyl-4-isopropylpiperazine
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2015_03
COC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccnc(N4CCN(C(=O)OC(C)(C)C)[C@H](C)C4)n3)sc2c1-c1ccc(Cl)cc1
Reaction #966790
(R)-tert-butyl 4-(4-(6-((S)-1-tert-butoxy-2-methoxy-2-oxoethyl)-7-(4-chlorophenyl)-5-methylbenzo[d]thiazol-2-yl)pyrimidin-2-yl)-2-methylpiperazine-1-carboxylate
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2015_03
Seite 1Weiter