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O=C(O)CCC(=O)c1ccccc1

CCOC(=O)C(=O)C(=NO)C(=O)c1c(C)cc(C)cc1C
Reaction #1249
semi-solid
DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)c1nn(C)c(-c2c(C)cc(C)cc2C)c1N
Reaction #1250
title compound
Ausbeute 78.9%DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)[C@H](CC(=O)c1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)OC(C)(C)C.O=C(O)/C=C\C(=O)O
Reaction #4464
product
Ausbeute 60.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C(O)c1cc(-c2ccc(C(F)(F)F)cc2)n[nH]c1=O
Reaction #8042
title compound
Ausbeute 91.4%DOI: 10.6084/m9.figshare.5104873.v1
CCCC(CC(=O)c1ccc(-c2ccc([N+](=O)[O-])cc2)cc1)C(=O)OCC
Reaction #9624
ethyl 2-[2-(4′-nitro-1,1′-biphenyl-4-yl)-2-oxoethyl]pentanoate
Ausbeute 48.0%DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)[C@@H]1CCCC[C@@H]1C(=O)c1ccc(Br)cc1
Reaction #9634
methyl cis-2-(4-bromobenzoyl)cyclohexane-carboxylate
Ausbeute 42.1%DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)[C@@H]1CCCC[C@@H]1C(=O)c1ccc(-c2ccc(N)cc2)cc1
Reaction #9635
methyl cis-2-[(4′-amino-1,1′-biphenyl-4-yl)carbonyl]cyclohexanecarboxylate
DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)C(C)(C)CC(=O)c1ccc(-c2ccc(N)c(F)c2)cc1
Reaction #9651
methyl 4-(4′-amino-3′-fluoro-1,1′-biphenyl-4-yl)-2,2-dimethyl-4-oxobutanoate
Ausbeute 89.4%DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)C(C)(C)CC(=O)c1ccc(-c2ccc(N)c(OC)c2)cc1
Reaction #9653
methyl 4-(4′-amino-3′-methoxy-1,1′-biphenyl-4-yl)-2,2-dimethyl-4-oxobutanoate
Ausbeute 67.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #9658
solid
Ausbeute 93.0%DOI: 10.6084/m9.figshare.5104873.v1
COCCC(CC(=O)c1ccc(-c2ccc(Nc3nc4ccccc4s3)cc2)cc1)C(=O)O
Reaction #9691
4-[4′-(1,3-benzothiazol-2-ylamino)-1,1′-biphenyl-4-yl]-2-(2-methoxyethyl)-4-oxobutanoic acid
Ausbeute 31.0%DOI: 10.6084/m9.figshare.5104873.v1
CCCCOC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(-c2ccc(Nc3nc4ccc(OC)cc4s3)c(F)c2)cc1
Reaction #9693
butyl (1R,2R)-2-({3′-fluoro-4′-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-1,1′-biphenyl-4-yl}carbonyl)cyclopentanecarboxylate
Ausbeute 65.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2nc(Nc3ccc(-c4ccc(C(=O)[C@@H]5CCC[C@H]5C(=O)O)cc4)cc3F)sc2c1
Reaction #9694
(1R,2R)-2-({3′-fluoro-4′-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-1,1′-biphenyl-4-yl}carbonyl)cyclopentanecarboxylic acid
Ausbeute 30.0%DOI: 10.6084/m9.figshare.5104873.v1
Cc1cccc2oc(Nc3ccc(-c4ccc(C(=O)CC(C)(C)C(=O)O)cc4)cc3)nc12
Reaction #9699
2,2-dimethyl-4-{4′-[(4-methyl-1,3-benzoxazol-2-yl)amino]-1,1′-biphenyl-4-yl}4-oxobutanoic acid
Ausbeute 32.1%DOI: 10.6084/m9.figshare.5104873.v1
O=C(O)[C@@H]1CCC[C@H]1C(=O)c1ccc(-c2ccc(Nc3nc4ccc(Cl)cc4s3)c(F)c2)cc1
Reaction #9706
desired product
Ausbeute 60.0%DOI: 10.6084/m9.figshare.5104873.v1
Cc1ccc2nc(Nc3ccc(-c4ccc(C(=O)[C@@H]5CCC[C@H]5C(=O)O)cc4)cc3)sc2c1
Reaction #9708
trans-2-({4′-[(6-methyl-1,3-benzothiazol-2-yl)amino]-1,1′-biphenyl-4-yl}carbonyl)-cyclopentanecarboxylic acid
Ausbeute 74.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C(O)[C@@H]1CCC[C@H]1C(=O)c1ccc(-c2ccc(Nc3nc4ccc(OC(F)(F)F)cc4s3)c(F)c2)cc1
Reaction #9710
desired compound
Ausbeute 80.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C(O)[C@@H]1CCC[C@H]1C(=O)c1ccc(-c2ccc(Nc3nc4ccc(F)cc4s3)c(F)c2)cc1
Reaction #9711
desired product
Ausbeute 77.0%DOI: 10.6084/m9.figshare.5104873.v1
Cc1ccc2oc(Nc3ccc(-c4ccc(C(=O)[C@@H]5CCC[C@H]5C(=O)O)cc4)cc3)nc2c1
Reaction #9712
(1R,2R)-2-({4′-[(5-methyl-1,3-benzoxazol-2-yl)amino]-1,1′-biphenyl-4-yl}carbonyl)cyclopentanecarboxylic acid
Ausbeute 17.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C(O)[C@@H]1CCCC[C@H]1C(=O)c1ccc(-c2ccc(Nc3nc4ccc(Cl)cc4s3)cc2)cc1
Reaction #9714
trans-2-({4′-[(6-chloro-1,3-benzothiazol-2-yl)amino]-1,1′-biphenyl-4-yl}carbonyl)cyclohexanecarboxylic acid
Ausbeute 15.5%DOI: 10.6084/m9.figshare.5104873.v1
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