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21284

CCOC(=O)c1cn2c(Br)ccc2cn1
Reaction #53439
ethyl 6-bromopyrrolo[1,2-a]pyrazine-3-carboxylate
Ausbeute 57.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C(N[C@H]1CN2CCC1CC2)c1cn2c(Br)ccc2cn1
Reaction #53440
N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-6-bromopyrrolo[1,2-a]pyrazine-3-carboxamide
DOI: 10.6084/m9.figshare.5104873.v1
CC#Cc1ccc2cnc(C(=O)N[C@H]3CN4CCC3CC4)cn12.O=C(O)C(O)C(O)C(=O)O
Reaction #53441
N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-6-prop-1-ynylpyrrolo[1,2-a]pyrazine-3-carboxamide Tartrate
Ausbeute 5.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C(N[C@H]1CN2CCC1CC2)c1cn2c(C#CCO)ccc2cn1.O=C(O)C(O)C(O)C(=O)O
Reaction #53442
N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-6-(3-hydroxyprop-1-ynyl)pyrrolo [1,2-a]pyrazine-3-carboxamide Tartrate
Ausbeute 24.0%DOI: 10.6084/m9.figshare.5104873.v1
N#Cc1ccc2cnc(C(=O)N[C@H]3CN4CCC3CC4)cn12.O=C(O)C(O)C(O)C(=O)O
Reaction #53443
N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-6-cyanopyrrolo[1,2-a]pyrazine-3-carboxamide Tartrate
Ausbeute 47.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc(-c2cn3c(Br)ccc3c(=O)[nH]2)cc1
Reaction #164537
6-bromo-3-(4-methoxy-phenyl)-2H-pyrrolo[1,2-a]pyrazin-1-one
Ausbeute 56.8%DOI: 10.6084/m9.figshare.5104873.v1
Cc1ccc2c(=O)[nH]c(-c3ccc(C(F)(F)F)cc3)cn12
Reaction #164542
6-methyl-3-(4-trifluoromethyl-phenyl)-2H-pyrrolo[1,2-a]pyrazin-1-one
Ausbeute 34.2%DOI: 10.6084/m9.figshare.5104873.v1
O=c1[nH]c(-c2ccc(C(F)(F)F)cc2)cn2c(Br)ccc12
Reaction #164549
6-bromo-3-(4-trifluoromethyl-phenyl)-2H-pyrrolo[1,2-a]pyrazin-1-one
Ausbeute 97.4%DOI: 10.6084/m9.figshare.5104873.v1
Cc1nccn2c(Br)ccc12
Reaction #320633
title compound
Ausbeute 80.0%DOI: 10.6084/m9.figshare.5104873.v1
Cc1nccn2c(C#N)ccc12
Reaction #320634
title compound
Ausbeute 78.1%DOI: 10.6084/m9.figshare.5104873.v1
NCCSc1ccc2cnccn12
Reaction #320638
title compound
Ausbeute 76.5%DOI: 10.6084/m9.figshare.5104873.v1
OCCSc1ccc2cnccn12
Reaction #320639
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)c1cn2c(Br)ccc2cn1
Reaction #767750
DOI: 10.1039/C8SC04228D