Teilstruktursuche

17397

CCOC(=O)C12CC1C=CCCCCCC(NC(=O)OC(C)(C)C)C(=O)N1CC(O[Si](C)(C)C(C)(C)C)CC1C(=O)N2

Reaction #46089

14-tert-butoxycarbonylamino-18-(tert-butyl-dimethyl-silanyloxy)-2,15-dioxo-3,16-diaza-tricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxylic acid ethyl ester

Ausbeute 96.3%DOI: 10.6084/m9.figshare.5104873.v1

CC(C)(C)OC(=O)NC1CCCCCC=CC2CC2(C(=O)O)NC(=O)C2CC(O[Si](C)(C)C(C)(C)C)CN2C1=O

Reaction #46090

14-tert-butoxycarbonylamino-18-(tert-butyl-dimethyl-silanyloxy)-2,15-dioxo-3,16-diaza-tricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxylic acid

Ausbeute 84.0%DOI: 10.6084/m9.figshare.5104873.v1

COc1c2c(c3n(c1=O)CCC(N1CCCC1)CN(C)C3=O)CCN(Cc1ccc(F)c(Cl)c1)C2=O

Reaction #46303

DOI: 10.6084/m9.figshare.5104873.v1

CN1CC(=O)CCn2c(c3c(c(O)c2=O)C(=O)N(Cc2ccc(F)c(Cl)c2)CC3)C1=O

Reaction #46304

DOI: 10.6084/m9.figshare.5104873.v1

Reaction #75560

Ausbeute 67.1%DOI: 10.6084/m9.figshare.5104873.v1

CCC(COc1ccc2c(=O)n(-c3ccc(N4CC[C@@H](N5CCCC5)C4)c(F)c3)ccc2c1)OC

Reaction #156635

2-((R)-4-[1,3′]Bipyrrolidinyl-1′-yl-3-fluorophenyl)-6-(2-methoxy-butoxy)-2H-isoquinolin-1-one

DOI: 10.6084/m9.figshare.5104873.v1

$CCC/C=C\c1ccc2c(=O)n(-c3ccc(N4CC[C@@H](N5CCCC5)C4)c(F)c3)ccc2c1$

Reaction #156641

2-((R)-4-[1,3′]Bipyrrolidinyl-1′-yl-3-fluorophenyl)-6-((Z)-pent-1-enyl)-2H-isoquinolin-1-one

DOI: 10.6084/m9.figshare.5104873.v1

CCC[C@H](O)[C@H](O)c1ccc2c(=O)n(-c3ccc(N4CC[C@@H](N5CCCC5)C4)c(F)c3)ccc2c1

Reaction #156642

2-((R)-4-[1,3′]Bipyrrolidinyl-1′-yl-3-fluorophenyl)-6-((1R*,2S*)-1,2-dihydroxy-pentyl)-2H-isoquinolin-1-one

DOI: 10.6084/m9.figshare.5104873.v1

CC(CC(C)(C)O)Oc1ccc2c(=O)n(-c3ccc(N4CC[C@@H](N5CCCC5)C4)c(F)c3)ccc2c1

Reaction #156706

2-((R)-4-[1,3′]Bipyrrolidinyl-1′-yl-3-fluoro-phenyl)-6-(3-hydroxy-1,3-dimethyl-butoxy)-2H-isoquinolin-1-one

DOI: 10.6084/m9.figshare.5104873.v1

O=c1c2ccc(OCC3OCCO3)cc2ccn1-c1ccc(N2CC[C@@H](N3CCCC3)C2)c(F)c1

Reaction #156707

2-((R)-4-[1,3′]Bipyrrolidinyl-1′-yl-3-fluoro-phenyl)-6-([1,3]dioxolan-2-ylmethoxy)-2H-isoquinolin-1-one

DOI: 10.6084/m9.figshare.5104873.v1

C#Cc1ccc(-c2cnc(C3CCCN3C(=O)C(NC(=O)OC)C(C)C)[nH]2)cc1

Reaction #158901

(1-{2-[5-(4-ethynyl-phenyl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester

Ausbeute 100.0%DOI: 10.6084/m9.figshare.5104873.v1

COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(Br)cc2)n1COCC[Si](C)(C)C)C(C)C

Reaction #158963

(1-{2-[5-(4-bromo-phenyl)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester

Ausbeute 71.4%DOI: 10.6084/m9.figshare.5104873.v1

COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(N3CCN(C(=O)OCc4ccccc4)CC3)cc2)n1COCC[Si](C)(C)C)C(C)C

Reaction #158966

4-{4-[2-[1-(2-methoxycarbonylamino-3-methyl-butyryl)-pyrrolidin-2-yl]-3-(2-trimethylsilanyl-ethoxymethyl)-3H-imidazol-4-yl]-phenyl}-piperazine-1-carboxylic acid benzyl ester

Ausbeute 13.0%DOI: 10.6084/m9.figshare.5104873.v1

COC(=O)NC(C(=O)N1CCCC1c1ncc(C#Cc2ccc(-c3cnc(C4CCCN4C(=O)C(NC(=O)OC)C(C)C)[nH]3)cc2)[nH]1)C(C)C

Reaction #159026

(1-{2-[5-(4-{2-[1-(2-Methoxycarbonylamino-3-methyl-butyryl)-pyrrolidin-2-yl]-3H-imidazol-4-yl}-phenylethynyl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester

Ausbeute 24.3%DOI: 10.6084/m9.figshare.5104873.v1

COC(=O)[C@@H]1C[C@@]2(CN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCCN1C(C)C)C1CCCCC1)C(C)(C)C)C(C)(C)C21CCC1

Reaction #164443

DOI: 10.6084/m9.figshare.5104873.v1

C#Cc1ccc(-c2cnc(C3CCCN3C(=O)C(NC(=O)OC)C(C)C)[nH]2)cc1

Reaction #166856

(1-{2-[5-(4-ethynyl-phenyl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester

Ausbeute 100.0%DOI: 10.6084/m9.figshare.5104873.v1

COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(Br)cc2)n1COCC[Si](C)(C)C)C(C)C

Reaction #166917

(1-{2-[5-(4-bromo-phenyl)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester

Ausbeute 71.4%DOI: 10.6084/m9.figshare.5104873.v1

COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(N3CCN(C(=O)OCc4ccccc4)CC3)cc2)n1COCC[Si](C)(C)C)C(C)C

Reaction #166920

4-{4-[2-[1-(2-methoxycarbonylamino-3-methyl-butyryl)-pyrrolidin-2-yl]-3-(2-trimethylsilanyl-ethoxymethyl)-3H-imidazol-4-yl]-phenyl}-piperazine-1-carboxylic acid benzyl ester

Ausbeute 13.0%DOI: 10.6084/m9.figshare.5104873.v1

COC(=O)NC(C(=O)N1CCCC1c1ncc(C#Cc2ccc(-c3cnc(C4CCCN4C(=O)C(NC(=O)OC)C(C)C)[nH]3)cc2)[nH]1)C(C)C

Reaction #166976

(1-{2-[5-(4-{2-[1-(2-Methoxycarbonylamino-3-methyl-butyryl)-pyrrolidin-2-yl]-3H-imidazol-4-yl}-phenylethynyl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester

Ausbeute 24.3%DOI: 10.6084/m9.figshare.5104873.v1

COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1ncc(-c2ccc(-c3ccc(-c4cnc([C@@H]5CCCN5C(=O)[C@@H](Nc5cccnc5)C(C)C)[nH]4)cc3)cc2)[nH]1)C(C)C

Reaction #167563

Ausbeute 56.4%DOI: 10.6084/m9.figshare.5104873.v1

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