Поиск по сходству

420175

CC(=O)c1nc(C(F)(F)F)n2c1CN(C(=O)OC(C)(C)C)CC2
Reaction #195288
DOI: 10.1039/C8SC04228D
CNC(=O)C(NC(=O)c1nc(Br)n2c1CN(C(=O)OC(C)(C)C)CC2)C(C)(C)C
Reaction #255269
DOI: 10.1039/C8SC04228D
CC(C)(C)OC(=O)N1CCn2c(C(F)(F)F)nc(Br)c2C1
Reaction #308659
1-bromo-3-trifluoromethyl-5,6-dihydro-8H-imidazo[1,5-a]pyrazine-7-carboxylic acid tert-butyl ester
Выход 57.8%DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1nc(C(F)(F)F)n2c1CN(C(=O)OC(C)(C)C)CC2
Reaction #308660
3-trifluoromethyl-5,6-dihydro-8H-imidazo[1,5-a]pyrazine-1,7-dicarboxylic acid 7-tert-butyl ester 1-methyl ester
Выход 67.8%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N1CCn2c(C(F)(F)F)nc(C(=O)O)c2C1
Reaction #308661
3-trifluoromethyl-5,6-dihydro-8H-imidazo[1,5-a]pyrazine-1,7-dicarboxylic acid 7-tert-butyl ester
Выход 108.5%DOI: 10.6084/m9.figshare.5104873.v1
CON(C)C(=O)c1nc(C(F)(F)F)n2c1CN(C(=O)OC(C)(C)C)CC2
Reaction #308662
1-(methoxy-methyl-carbamoyl)-3-trifluoromethyl-5,6-dihydro-8H-imidazo[1,5-a]pyrazine-7-carboxylic acid tert-butyl ester
Выход 100.9%DOI: 10.6084/m9.figshare.5104873.v1
CC(=O)c1nc(C(F)(F)F)n2c1CN(C(=O)OC(C)(C)C)CC2
Reaction #308663
1-acetyl-3-trifluoromethyl-5,6-dihydro-8H-imidazo[1,5-a]pyrazine-7-carboxylic acid tert-butyl ester
Выход 91.1%DOI: 10.6084/m9.figshare.5104873.v1
CC(=O)c1nc(C(F)(F)F)n2c1CNCC2
Reaction #308664
1-(3-trifluoromethyl-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazin-1-yl)-ethanone
DOI: 10.6084/m9.figshare.5104873.v1
CC1c2c(C(=O)O)nc(C(F)(F)F)n2CCN1C(=O)OC(C)(C)C
Reaction #308688
8-methyl-3-trifluoromethyl-5,6-dihydro-8H-imidazo[1,5-a]pyrazine-1,7-dicarboxylic acid 7-tert-butyl ester
Выход 24.3%DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1nc(-c2ccccc2)n2c1CN(C(=O)OC(C)(C)C)CC2
Reaction #373139
DOI: 10.1039/C8SC04228D
CNC(=O)C(NC(=O)c1nc(Br)n2c1CN(C(=O)OC(C)(C)C)CC2)C(C)(C)C
Reaction #396191
DOI: 10.1039/C8SC04228D
CC(C)(C)OC(=O)N1CCCn2c(-c3ccccc3)nc(C(=O)O)c2C1
Reaction #403277
DOI: 10.1039/C8SC04228D
CNC(=O)C(NC(=O)c1nc(C(=O)c2ccccc2)n2c1CN(C(=O)OC(C)(C)C)CC2)C(C)(C)C
Reaction #404785
DOI: 10.1039/C8SC04228D
COC(=O)c1nc(Br)n2c1CN(C(=O)OC(C)(C)C)CC2
Reaction #623098
Intermediate 1H
Выход 95.1%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N1CCn2c(Br)nc(C(=O)O)c2C1
Reaction #623099
Intermediate 1I
Выход 76.0%DOI: 10.6084/m9.figshare.5104873.v1
CNC(=O)[C@@H](NC(=O)c1nc(Br)n2c1CN(C(=O)OC(C)(C)C)CC2)C(C)(C)C
Reaction #623100
Intermediate 1J
Выход 80.4%DOI: 10.6084/m9.figshare.5104873.v1
CNC(=O)[C@@H](NC(=O)c1nc(-c2ccccc2)n2c1CN(C(=O)OC(C)(C)C)CC2)C(C)(C)C
Reaction #623101
Compound 1
Выход 76.1%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #623103
compounds 22-29
DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1nc(Br)n2c1CN(C(=O)OC(C)(C)C)CC2
Reaction #623104
Intermediate 1H
Выход 60.0%DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1nc(-c2ccccc2)n2c1CN(C(=O)OC(C)(C)C)CC2
Reaction #623105
Intermediate 3A
Выход 70.0%DOI: 10.6084/m9.figshare.5104873.v1
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