intermediate b

CCc1ccc2c(n1)N1[C@H](C2)CN(C(=O)OC(C)(C)C)C[C@H]1C
Reaction #12012
product
수율 89.5%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]2Cc3ccc(C(F)(F)F)nc3N21
Reaction #12013
desired compound
수율 27.7%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]2Cc3ccc(C4CC4)nc3N21
Reaction #12014
desired product
수율 35.2%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CCOC(=O)C=Cc1ccc2c(n1)N1[C@H](C2)CN(C(=O)OC(C)(C)C)C[C@H]1C
Reaction #12015
desired compound
수율 91.2%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]2Cc3ccc(C#N)nc3N21
Reaction #12018
desired compound
수율 98.4%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
COC(=O)c1ccc2c(n1)N1[C@H](C2)CN(C(=O)OC(C)(C)C)C[C@H]1C
Reaction #12019
product
수율 74.4%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C[C@@H]1CNC(=O)c2cc3cccnc3n21
Reaction #12024
(R)-4-Methyl-3,4-dihydro-2H-2,4a,5-triaza-fluoren-1-one
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C[C@@H]1CN(C(=O)OC(C)(C)C)CC2Cc3cccnc3N21
Reaction #12025
(R)-4-Methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]2Cc3ccc(N=C(c4ccccc4)c4ccccc4)nc3N21
Reaction #12026
product
수율 94.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]2Cc3ccc(OCc4ccccc4)nc3N21
Reaction #12029
(4R,9aR)-6-Benzyloxy-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CCOc1ccc2c(n1)N1[C@H](C2)CN(C(=O)OC(C)(C)C)C[C@H]1C
Reaction #12032
(4R,9aR)-6-Ethoxy-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic tert-butyl ester
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]2Cc3ccc(OCCO)nc3N21
Reaction #12033
(4R,9aR)-6-(2-Hydroxy-ethoxy)-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
COCCOc1ccc2c(n1)N1[C@H](C2)CN(C(=O)OC(C)(C)C)C[C@H]1C
Reaction #12034
(4R,9aR)-6-(2-Methoxy-ethoxy)-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CC(O)c1ccc2c(n1)N1[C@H](C2)CN(C(=O)OC(C)(C)C)C[C@H]1C
Reaction #12042
(4R,9aR)-6-(1-(RS)-Hydroxy-ethyl)-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]2Cc3ccc(C(C)(C)O)nc3N21
Reaction #12048
compound
수율 24.4%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]2Cc3ccc(C(C)(O)CCCCl)nc3N21
Reaction #12051
compound
수율 50.9%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CCSc1ccc2c(n1)N1[C@H](C2)CN(C(=O)OC(C)(C)C)C[C@H]1C
Reaction #1359356
title compound
수율 53.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2007_04
C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]2Cc3ccc(C(O)CO[Si](C)(C)C(C)(C)C)nc3N21
Reaction #2072904
(4R,9aR)-6-[2-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-ethyl]-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester
수율 46.5%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2009_06