MeTHF

COC[C@@H]1Cn2cc(-c3nc(Nc4ccnn4C)ncc3C)nc2C(=O)N1Cc1ccc(F)c(F)c1
Reaction #685
수율 55.0%750 AstraZeneca ELN dataset
CC(C)C[C@@H](C(=O)O)N1CC(Oc2ccccc2Cl)=CC1=O
Reaction #47276
(S)-2-[4-(2-chloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid
수율 67.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
O=Cc1c(F)cc(C(=O)O)cc1F
Reaction #69374
title compound
수율 35.6%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_09
Cn1cc(B2OC(C)(C)C(C)(C)O2)c(-c2ccc(F)cc2)n1
Reaction #70155
3-(4-fluorophenyl)-1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_09
CCOC(CNCC1CCCCC1)OCC
Reaction #71532
N-cyclohexylmethyl-(2,2-diethoxyethyl)amine
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_09
O=CCN(CC1CCCCC1)C(=O)OCc1ccccc1
Reaction #71533
crude title intermediate
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_09
COc1ccc(CN(c2nncs2)S(=O)(=O)c2cc(Cl)c(F)cc2F)c(OC)c1
Reaction #74594
title compound
수율 58.5%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_09
COc1ccc(CNc2nncs2)c(OC)c1
Reaction #74596
title compound
수율 73.5%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_09
CC(=O)Oc1ccc(C(F)(F)F)cc1-c1ccoc1
Reaction #74683
title product
수율 86.6%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_09
COc1c(-c2ccc3cc(NS(C)(=O)=O)ccc3c2)cc(-n2ccc(=O)[nH]c2=O)cc1C(C)(C)C
Reaction #86682
title compound
수율 94.6%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_09
COc1c(-c2ccc3cc(NS(C)(=O)=O)ccc3c2)cc(-n2ccc(=O)[nH]c2=O)cc1C(C)(C)C
Reaction #86687
N-(6-(3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)naphthalen-2-yl)methanesulfonamide
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_09
COc1c(-c2ccc3cc(NS(C)(=O)=O)ccc3c2)cc(-n2ccc(=O)[nH]c2=O)cc1C(C)(C)C
Reaction #86688
N-(6-(3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)naphthalen-2-yl)methanesulfonamide
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_09
OC[C@@]12CO[C@@](c3ccc(Cl)c(Cc4ccc(O)cc4)c3)(O1)[C@H](O)[C@@H](O)[C@@H]2O
Reaction #87469
(1 S,2S,3S,4R,5S)-5-[4-chloro-3-(4-hydroxy-benzyl)-phenyl]-1-hydroxymethyl-6,8-dioxa-bicyclo[3.2.1]octane-2,3,4-triol
수율 69.7%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_09
OC[C@@]12CO[C@@](c3ccc(Cl)c(Cc4ccc(O)cc4)c3)(O1)[C@H](O)[C@@H](O)[C@@H]2O
Reaction #87489
(1S,2S,3S,4R,5S)-5-[4-chloro-3-(4-hydroxy-benzyl)-phenyl]-1-hydroxymethyl-6,8-dioxa-bicyclo[3.2.1]octane-2,3,4-triol
수율 69.7%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_09
O=C(Nc1ccccc1O)c1ccc(F)cc1
Reaction #87914
4-Fluoro-N-(2-hydroxyphenyl)-benzamide
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_09
CSc1cc(C#N)ccc1C(NC(=O)OC(C)(C)C)C1=C(Nc2cccc(C(F)(F)F)c2)CCCC1=O
Reaction #87921
{(4-Cyano-2-methylsulfanyl-phenyl)-[6-oxo-2-(3-trifluoromethyl-phenylamino)cyclohex-1-enyl]-methyl}-carbamic acid tert-butyl ester
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_09
CC(C)(C)OC(=O)NC(C1=C(Nc2cccc(C(F)(F)F)c2)CCCC1=O)c1ccc(C#N)cc1Br
Reaction #87930
{(2-Bromo-4-cyano-phenyl)-[6-oxo-2-(3-trifluoromethyl-phenylamino)-cyclohex-1-enyl]-methyl}-carbamic acid tert-butyl ester
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_09
C=CCC1CCCC1O
Reaction #88818
2-allylcyclopentanol
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_09
C=CCC1CC1OC(C)=O
Reaction #88819
racemic 2-allylcyclopropyl acetate
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_09
CSc1cccc(S)c1
Reaction #155414
title compound
수율 78.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
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