반응 #71533

반응 방정식

N-cyclohexylmethyl-(2-oxoethyl)-carbamic acid benzyl ester bisulfite

MeTHF

NaOH

→

crude title intermediate

N-cyclohexylmethyl-(2-oxoethyl)-carbamic acid benzyl ester

용매

water

반응 조건

후처리

1. 1
   workup.STIRRINGThe reaction mixture was stirred at room temperature for 45 min
2. 2
   기타The layers were separated

실험 절차

To a 100 mL flask was added N-cyclohexylmethyl-(2-oxoethyl)-carbamic acid benzyl ester bisulfite adduct (3.94 g, 1 mmol) and MeTHF (35 mL), followed by water (25 mL). The resulting slurry was stirred at room temperature for 5 min and 1 M NaOH (8 mL) was added. The reaction mixture was stirred at room temperature for 45 min. The layers were separated and the volume of the organic layer was reduced to ˜8 mL to provide the crude title intermediate.

출처