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1313206

O=C1OCc2c1c(Cl)nc1ccccc21

4-Chloro-furo[3,4-c]quinolin-3(1H)-one

DOI: 10.6084/m9.figshare.5104873.v1

COc1ccc2nc3ccccc3c(C(=O)O)c2c1

Reaction #11296

2-Methoxy-acridine-9-carboxylic acid

DOI: 10.6084/m9.figshare.5104873.v1

COC(=O)c1cc(=O)n(CC=O)c2cc(OC)ccc12

Reaction #68045

methyl 7-methoxy-2-oxo-1-(2-oxoethyl)-1,2-dihydroquinoline-4-carboxylate

수율 116.0%DOI: 10.6084/m9.figshare.5104873.v1

COC(=O)c1cc(=O)n(CCN2CCC(N(Cc3ccc4c(c3)OCCO4)C(=O)OC(C)(C)C)CC2)c2cc(OC)ccc12

Reaction #68046

methyl 1-(2-(4-((tert-butoxycarbonyl) (2,3-dihydro-1,4-benzodioxin-6-ylmethyl)amino)piperidin-1-yl)ethyl)-7-methoxy-2-oxo-1,2-dihydroquinoline-4-carboxylate

수율 66.6%DOI: 10.6084/m9.figshare.5104873.v1

COC(=O)c1cc(=O)n(CCN2CCC(NCc3ccc4c(c3)OCCO4)CC2)c2cc(OC)ccc12

Reaction #68047

methyl 1-(2-(4-((2,3-dihydro-1,4-benzodioxin-6-ylmethyl)amino)piperidin-1-yl)ethyl)-7-methoxy-2-oxo-1,2-dihydroquinoline-4-carboxylate

수율 57.5%DOI: 10.6084/m9.figshare.5104873.v1

COc1ccc2c(C(=O)O)cc(=O)n(CCN3CCC(NCc4ccc5c(c4)OCCO5)CC3)c2c1

Reaction #68048

1-(2-(4-((2,3-dihydro-1,4-benzodioxin-6-ylmethyl)amino)piperidin-1-yl)ethyl)-7-methoxy-2-oxo-1,2-dihydroquinoline-4-carboxylic acid

수율 34.3%DOI: 10.6084/m9.figshare.5104873.v1

CNC(=O)c1cc(=O)n(CCN2CCC(N(Cc3ccc4c(c3)OCCO4)C(=O)OC(C)(C)C)CC2)c2cc(OC)ccc12

Reaction #68060

tert-butyl (2,3-dihydro-1,4-benzodioxin-6-ylmethyl)(1-(2-(7-methoxy-4-((methylamino)carbonyl)-2-oxoquinolin-1(2H)-yl)ethyl)piperidin-4-yl)carbamate

수율 93.9%DOI: 10.6084/m9.figshare.5104873.v1

CNC(=O)c1cc(=O)n(CCN2CCC(NCc3ccc4c(c3)OCCO4)CC2)c2cc(OC)ccc12

Reaction #68061

1-(2-(4-((2,3-dihydro-1,4-benzodioxin-6-ylmethyl)amino)piperidin-1-yl)ethyl)-7-methoxy-N-methyl-2-oxo-1,2-dihydroquinoline-4-carboxamide

수율 70.3%DOI: 10.6084/m9.figshare.5104873.v1

CNC(=O)c1cc(=O)n(CCN2CCC(NCc3ccc(C)c(F)c3)CC2)c2ccccc12

Reaction #68092

1-(2-(4-((3-fluoro-4-methylbenzyl)amino)piperidin-1-yl)ethyl)-N-methyl-2-oxo-1,2-dihydroquinoline-4-carboxamide

DOI: 10.6084/m9.figshare.5104873.v1

COC(=O)c1cc(=O)n(CCNC2CCN(Cc3ccc4c(c3)OCCO4)CC2)c2cc(OC)ccc12

Reaction #68148

methyl 1-(2-(1-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)piperidin-4-ylamino)ethyl)-7-methoxy-2-oxo-1,2-dihydroquinoline-4-carboxylate

수율 70.5%DOI: 10.6084/m9.figshare.5104873.v1

COC(=O)c1cc(=O)n(CCNC2CCN(Cc3ccc4c(c3)OCCO4)CC2)c2cc(OC)ccc12.Cl

Reaction #68149

methyl 1-(2-(1-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)piperidin-4-ylamino)ethyl)-7-methoxy-2-oxo-1,2-dihydroquinoline-4-carboxylate hydrochloride

DOI: 10.6084/m9.figshare.5104873.v1

CNC(=O)c1cc(=O)n(CCN2CCC(NCc3ccc4ccccc4c3)CC2)c2cc(OC)ccc12

Reaction #68227

7-methoxy-N-methyl-1-(2-(4-((naphthalen-2-ylmethyl)amino)piperidin-1-yl)ethyl)-2-oxo-1,2-dihydroquinoline-4-carboxamide

수율 119.6%DOI: 10.6084/m9.figshare.5104873.v1

CNC(=O)c1cc(=O)n(CCN2CCC(NCc3ccc4ccccc4c3)CC2)c2cc(OC)ccc12.Cl

Reaction #68228

7-methoxy-N-methyl-1-(2-(4-((naphthalen-2-ylmethyl)amino)piperidin-1-yl)ethyl)-2-oxo-1,2-dihydroquinoline-4-carboxamide hydrochloride

DOI: 10.6084/m9.figshare.5104873.v1

O=C/C=C/c1ccnc2ccccc12

Reaction #78846

DOI: 10.6084/m9.figshare.5104873.v1

CCOC(=O)c1cc(Sc2ccc(NC(=S)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)nc2ccccc12

Reaction #83339

수율 89.0%DOI: 10.6084/m9.figshare.5104873.v1

N[C@@]1(C(=O)O)CN(Cc2ccnc3ccccc23)C[C@@H]1CCCB(O)O

Reaction #89643

(3R,4S)-3-amino-4-(3-boronopropyl)-1-(quinolin-4-ylmethyl)pyrrolidine-3-carboxylic acid

수율 27.4%DOI: 10.6084/m9.figshare.5104873.v1

OC(CCC1CCNCC1)c1cc(-c2ccccc2)nc2ccccc12

Reaction #93495

1-(2-PHENYL-4-QUINOLYL)-3-(4-PIPERIDYL)-1-PROPANOL

DOI: 10.6084/m9.figshare.5104873.v1

OC(CCC1CCNCC1)c1cc(C2CCCCC2)nc2ccccc12

Reaction #93500

1-(2-cyclohexyl-4-quinolyl)-3-(4-piperidyl)-1-propanol

수율 28.0%DOI: 10.6084/m9.figshare.5104873.v1

$COCCn1c(C)c(C)s/c1=N\C(=O)c1cc(Cl)nc2ccccc12$

Reaction #165626

수율 35.0%DOI: 10.6084/m9.figshare.5104873.v1

CNC(=O)c1cc(=O)n(CCN2CCC(N(Cc3ccc4c(c3)OCCO4)C(=O)OC(C)(C)C)CC2)c2cc(OC)ccc12

Reaction #176570

DOI: 10.1039/C8SC04228D

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