반응 #93495

반응 방정식

1-(2-phenyl-4-quinolyl)-3-(4-piperidyl)-1-propanone

sodium borohydride

→

1-(2-PHENYL-4-QUINOLYL)-3-(4-PIPERIDYL)-1-PROPANOL

용매

methanol

반응 조건

후처리

1. 1
   기타After recrystallization of the crude product in isopropanol, 7 g of 1-(2-phenyl-4-quinolyl)-3-(4-piperidyl)-1-propanol (racemic)
2. 2
   기타were obtained

실험 절차

The operation was as in Example 1, except that 14 g of 1-(2-phenyl-4-quinolyl)-3-(4-piperidyl)-1-propanone and 2.3 g of sodium borohydride in 300 ml of methanol were used. After recrystallization of the crude product in isopropanol, 7 g of 1-(2-phenyl-4-quinolyl)-3-(4-piperidyl)-1-propanol (racemic) were obtained, which melted at 162° C.

출처