intermediate 1

CC(C)N1CCC(Oc2ccc3[nH]c(C(=O)N4CCOCC4)cc3c2)CC1
Reaction #48119
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3S(=O)(=O)c2ccc(F)cc2)CC1
Reaction #48120
desired product
収率 60.1%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3Cc2ccc(F)cc2)CC1
Reaction #48122
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
COC(=O)n1c(C(=O)N2CCC(F)(F)CC2)cc2cc(OC3CCN(C(C)C)CC3)ccc21
Reaction #48123
desired product
収率 15.7%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3CC#N)CC1
Reaction #48124
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3-c2cc(F)cc(F)c2)CC1
Reaction #48125
desired product
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3-c2cccc(OC(F)(F)F)c2)CC1
Reaction #48126
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3-c2ccc(OC(F)(F)F)cc2)CC1
Reaction #48127
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3-c2ccnc(Cl)c2)CC1
Reaction #48128
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3-c2ccc(Cl)nc2)CC1
Reaction #48129
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
COc1ccccc1-n1c(C(=O)N2CCC(F)(F)CC2)cc2cc(OC3CCN(C(C)C)CC3)ccc21
Reaction #48130
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3-c2ccc(F)cc2)CC1
Reaction #48131
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3-c2cccc(F)c2)CC1
Reaction #48132
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3-c2cccc(Cl)c2)CC1
Reaction #48133
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
COc1cccc(-n2c(C(=O)N3CCC(F)(F)CC3)cc3cc(OC4CCN(C(C)C)CC4)ccc32)c1
Reaction #48134
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3-c2ccc(C(F)(F)F)cc2)CC1
Reaction #48135
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3-c2ccccc2)CC1
Reaction #48136
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
Cc1ccc(-n2c(C(=O)N3CCC(F)(F)CC3)cc3cc(OC4CCN(C(C)C)CC4)ccc32)cc1
Reaction #48137
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3-c2ccc(Cl)cc2)CC1
Reaction #48138
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3-c2ccc(Cl)c(Cl)c2)CC1
Reaction #48139
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
1 ページ次のページ