Recherche de Sous-structure

40362

O=c1c(-c2ccc(F)cc2)c(-c2ccnc(Oc3ccccc3)n2)n2n1CC(N1CCOCC1)C2
Reaction #7744
desired product
Rendement 20.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #10417
ethyl acetate hexanes
DOI: 10.6084/m9.figshare.5104873.v1
O=c1c(-c2ccc(F)cc2)c(-c2ccnc(Oc3ccccc3)n2)n2n1CC(N1CCOCC1)C2
Reaction #50952
desired product
Rendement 20.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)NCCNc1nc(-c2ccc(C#N)cc2)cc(N2CCOCC2)n1
Reaction #60062
(tert-butoxy)-N-(2-{[4-(4-cyanophenyl)-6-morpholin-4-ylpyrimidin-2-yl]amino}ethyl)-carboxamide
DOI: 10.6084/m9.figshare.5104873.v1
CS(=O)(=O)OCc1cc(Oc2ccc3c(c2)CCN3C(=O)Nc2cccc(C(F)(F)F)c2)ncn1
Reaction #73382
title compound
DOI: 10.6084/m9.figshare.5104873.v1
O=Cc1cc(Oc2ccc3c(ccn3C(=O)Nc3cccc(C(F)(F)F)c3)c2)ncn1
Reaction #73387
title compound
DOI: 10.6084/m9.figshare.5104873.v1
C#CC(=O)N[C@H]1CCC[C@H]1Nc1ncc2cc(-c3c(F)ccc(OC)c3F)ccc2n1
Reaction #84636
N-((1S,2R)-2-((6-(2,6-difluoro-3-methoxyphenyl)quinazolin-2-yl)amino)cyclopentyl)propiolamide
Rendement 68.4%DOI: 10.6084/m9.figshare.5104873.v1
C#CC(=O)N[C@H]1CCC[C@H]1Nc1ncc2cc(-c3c(F)ccc(OCC)c3Cl)ccc2n1
Reaction #84640
N-((1S,2R)-2-((6-(2-chloro-3-ethoxy-6-fluorophenyl)quinazolin-2-yl)amino)cyclopentyl)propiolamide
Rendement 77.3%DOI: 10.6084/m9.figshare.5104873.v1
C#CC(=O)N[C@H]1CCC[C@H]1Nc1ncc2cc(-c3ccc(C(=O)NC4CC4)cc3OC)ccc2n1
Reaction #84645
N-cyclopropyl-3-methoxy-4-(2-(((1R,2S)-2-propiolamidocyclopentyl)amino)quinazolin-6-yl)benzamide
Rendement 69.0%DOI: 10.6084/m9.figshare.5104873.v1
Cn1c(=O)n(CCCO[Si](C)(C)C(C)(C)C)c(=O)c2cc(Oc3cccc(Cl)c3)ncc21
Reaction #88446
3-(3-(tert-butyldimethylsilyloxy)propyl)-6-(3-chlorophenoxy)-1-methylpyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione
Rendement 63.0%DOI: 10.6084/m9.figshare.5104873.v1
Cn1c(=O)n(CCCO[Si](C)(C)C(C)(C)C)c(=O)c2c(C(O)c3ccc(Cl)cc3)c(Oc3cccc(Cl)c3)ncc21
Reaction #88447
3-(3-(tert-butyldimethylsilyloxy)propyl)-6-(3-chlorophenoxy)-5-((4-chlorophenyl)(hydroxy)methyl)-1-methylpyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione
Rendement 29.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1cnc(N2CCC(N(C(=O)c3ccc(-c4cnco4)cc3)C3CC3)CC2)nc1
Reaction #156008
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CCCOc1cnc(N2CCC(N(C(=O)c3ccc(-c4cnco4)cc3)C3CC3)CC2)nc1
Reaction #156052
N-Cyclopropyl-4-oxazol-5-yl-N-[1-(5-propoxy-pyrimidin-2-yl)-piperidin-4-yl]-benzamide
DOI: 10.6084/m9.figshare.5104873.v1
CCOc1cnc(N2CCC(N(C(=O)c3ccc(-c4cnco4)cc3)C3CC3)CC2)nc1
Reaction #156053
title compound
DOI: 10.6084/m9.figshare.5104873.v1
COc1c(Cl)cc(F)c(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c1NNC(=O)C1CC1
Reaction #174632
DOI: 10.1039/C8SC04228D
CCOC(=O)NOCc1cc(-n2c(=O)cc(C(F)(F)F)n(N)c2=O)c(F)cc1Cl
Reaction #175381
DOI: 10.1039/C8SC04228D
CCSCCOC(=O)C(Br)=Cc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)ccc1Cl
Reaction #178591
DOI: 10.1039/C8SC04228D
N#Cc1c[nH]c2ccc(CCNC(=O)c3ccc(-c4ccnc(NCCCCCN5CCCCC5)n4)cc3)cc12
Reaction #179298
DOI: 10.1039/C8SC04228D
CCN1CCn2c(nc(C(=O)OC)c(O)c2=O)C(N(C)Cc2ccccc2)C1
Reaction #183703
DOI: 10.1039/C8SC04228D
COc1cc2[nH]c(N(C)Cc3cccc(OCCO)c3)nc(=O)c2c(OC)c1OC
Reaction #187407
DOI: 10.1039/C8SC04228D
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