5-methylpyrazin-2-amine

COC[C@H](C)Oc1cc(OCc2ccccc2)cc(C(=O)Nc2cnc(C)cn2)c1
Reaction #48796
desired compound
Rendimiento 98.2%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
Cc1cnc(NC(=O)c2cc(Oc3ccc(C(=O)N4CCC4)cc3F)cc(O[C@@H](C)CO[Si](C)(C)C(C)(C)C)c2)cn1
Reaction #48799
desired compound
Rendimiento 101.6%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
C[C@@H](CO[Si](C)(C)C(C)(C)C)Oc1cc(Oc2ccc(C(=O)N3CCC3)cc2Cl)cc(C(=O)Nc2cnccn2)c1
Reaction #48882
desired compound
Rendimiento 12.4%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
Cc1cnc(N)c(Br)n1
Reaction #95016
2-Amino-3-bromo-5-methylpyrazine
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-1982_08
COCC(C)Oc1cc(Oc2cnc(C(=O)N3CCC3)cn2)cc(C(=O)Nc2cnc(C)cn2)c1
Reaction #183513
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
COCC(C)Oc1cc(OCc2ccccc2)cc(C(=O)Nc2cnc(C)cn2)c1
Reaction #198851
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
COC(=O)c1ccc(NC(=O)Nc2cnc(C)cn2)c(OCc2cccnc2)c1
Reaction #223074
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
Cc1cnc(NC(=O)c2cc(OCc3ccccc3)cc(OC3CCOCC3)c2)cn1
Reaction #247495
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
COC(=O)c1cnc(Nc2cnc(C)cn2)cc1NCC1CCN(C(=O)OC(C)(C)C)CC1
Reaction #253356
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
COCC(C)Oc1cc(Oc2ccc3c(c2)OCCN(C)C3=O)cc(C(=O)Nc2cnc(C)cn2)c1
Reaction #267720
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
Cc1cnc(NC(=O)c2cc(Oc3ncc(C(=O)N4CCC4)cc3Cl)cc(OC(C)CO[Si](C)(C)C(C)(C)C)c2)cn1
Reaction #280162
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
Cc1cnc(NC(=O)Oc2ccccc2)cn1
Reaction #294796
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
Cc1cnc(NC(=O)c2cc(OCc3ccccc3)cc(OC3CCOC3)c2)cn1
Reaction #297602
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
Cc1cnc(N)c(Br)n1
Reaction #355118
2-Amino-3-bromo-5-methylpyrazine
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-1976_03
COCC(C)Oc1cc(OCc2ccccc2)cc(C(=O)Nc2cnc(C)cn2)c1
Reaction #396561
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
Cc1cnc(N)c(Br)n1
Reaction #448595
2-amino-3-bromo-5-methylpyrazine
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-1999_02
COC(=O)c1cnc(Nc2cnc(C)cn2)cc1NCC1CCN(C(=O)OC(C)(C)C)CC1
Reaction #471829
methyl 6-(5-methylpyrazin-2-ylamino)-4-(1-Boc-piperidin-4-ylmethylamino)nicotinate
Rendimiento 33.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_02
Cc1cnc(NC(=O)Oc2ccccc2)cn1
Reaction #505187
product
Rendimiento 68.7%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2012_01
COC[C@H](C)Oc1cc(Oc2cnc(C(=O)N3CCC3)cn2)cc(C(=O)Nc2cnc(C)cn2)c1
Reaction #505194
title compound
Rendimiento 62.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2012_01
COC[C@H](C)Oc1cc(Oc2cnc(C(=O)N3CCC3)cn2)cc(C(=O)Nc2cnc(C)cn2)c1
Reaction #505205
desired product
Rendimiento 85.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2012_01
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