Involved in 88 reactions

944

N#Cc1ccc(F)cc1N1CCNCC1
Reaction #414
Yield 0.0%750 AstraZeneca ELN dataset
N#Cc1ccc(Nn2cnnc2)cc1Br
Reaction #169960
4-(4H-1,2,4-Triazol-4-ylamino)-2-bromobenzonitrile
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
N#Cc1ccc(F)cc1-c1cc2ccccc2o1
Reaction #169964
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
N#Cc1ccc(F)cc1-c1ccco1
Reaction #169965
title compound
Yield 35.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
N#Cc1ccc(F)cc1-c1ccoc1
Reaction #169967
title compound
Yield 32.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1Nc1ccc(C#N)c(Br)c1
Reaction #171973
tert-butyl (1S,2R)-2-(3-bromo-4-cyanophenylamino)cyclohexylcarbamate
Yield 464.5%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
CC(C)C[C@@H](Nc1ccc(C#N)c(Br)c1)C(N)=O
Reaction #171986
(R)-2-(3-bromo-4-cyanophenylamino)-4-methylpentanamide
Yield 60.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
C[C@@H](Nc1ccc(C#N)c(Br)c1)C(N)=O
Reaction #171989
(R)-2-(3-bromo-4-cyanophenylamino)propanamide
Yield 69.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
N#Cc1ccc(N[C@H](Cc2ccccc2)C(N)=O)cc1Br
Reaction #171998
(R)-2-(3-bromo-4-cyanophenylamino)-3-phenylpropanamide
Yield 23.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
N#Cc1ccc(N[C@H](COCc2ccccc2)C(N)=O)cc1Br
Reaction #172001
(R)-3-(benzyloxy)-2-(3-bromo-4-cyanophenylamino)propanamide
Yield 17.6%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
N#Cc1ccc(N[C@H](CC2CCCCC2)C(N)=O)cc1Br
Reaction #172006
(R)-2-(3-bromo-4-cyanophenylamino)-3-cyclohexylpropanamide
Yield 63.4%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
COC[C@@H](CNc1ccc(C#N)c(Br)c1)NC(=O)OC(C)(C)C
Reaction #172025
(R)-tert-butyl 1-(3-bromo-4-cyanophenylamino)-3-methoxypropan-2-ylcarbamate
Yield 78.1%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
N#Cc1ccc(NC2CCCCNC2=O)cc1Br
Reaction #172055
2-bromo-4-(2-oxoazepan-3-ylamino)benzonitrile
Yield 50.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
N#Cc1ccc(N[C@H](Cc2c[nH]c3ccccc23)C(N)=O)cc1Br
Reaction #172060
(R)-2-(3-bromo-4-cyanophenylamino)-3-(1H-indol-3-yl)propanamide
Yield 31.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
N#Cc1ccc(N[C@H](Cc2cccs2)C(N)=O)cc1Br
Reaction #172075
(R)-2-(3-bromo-4-cyanophenylamino)-3-(thiophen-2-yl)propanamide
Yield 18.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
CC1(C)CC(=O)c2c(C(F)(F)F)nn(-c3ccc(C#N)c(Br)c3)c2C1
Reaction #190691
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
CC1C(C(C)(C)O)CCN1c1ccc(C#N)c(Br)c1
Reaction #225166
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
N#Cc1ccc(F)cc1C=O
Reaction #251160
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
N#Cc1ccc(F)cc1N1CCOC1=O
Reaction #292184
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
COC(=O)c1cccc2c1c1ccccc1n2-c1ccc(C#N)c(Br)c1
Reaction #299630
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
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