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N#Cc1ccc(-c2csc(N)n2)cc1

N#Cc1ccc(-c2csc(N3CCOC3=O)n2)cc1
Reaction #173
Ausbeute 0.0%
COC(=O)CCC(C)(C)Nc1nc(-c2ccc(C#N)cc2)cs1
Reaction #199225
DOI: 10.1039/C8SC04228D
NCc1ccc(-c2csc(NC(=O)C3CCCN3C(=O)OCc3ccccc3)n2)cc1
Reaction #212958
DOI: 10.1039/C8SC04228D
N#Cc1ccc(-c2csc(N3CCOC3=O)n2)cc1
Reaction #241943
DOI: 10.1039/C8SC04228D
CC1(C)COC(=O)N1c1nc(-c2ccc(C#N)cc2F)cs1
Reaction #250601
DOI: 10.1039/C8SC04228D
CC(C)(C=O)Nc1nc(-c2ccc(C#N)cc2)cs1
Reaction #259876
DOI: 10.1039/C8SC04228D
CC1(C)CN(Cc2ccccc2)C(=O)N1c1nc(-c2ccc(C#N)cc2)cs1
Reaction #299675
DOI: 10.1039/C8SC04228D
CC1(C)C=CC(=O)N1c1nc(-c2ccc(C#N)cc2)cs1
Reaction #371910
DOI: 10.1039/C8SC04228D
CC(=O)N=C1OCC(C)(C)N1c1nc(-c2ccc(C#N)cc2)cs1
Reaction #391338
DOI: 10.1039/C8SC04228D
CC1(C)OCCN1c1nc(-c2ccc(C#N)cc2)cs1
Reaction #749682
DOI: 10.1039/C8SC04228D
CC1(C)COC(=NC#N)N1c1nc(-c2ccc(C#N)cc2)cs1
Reaction #762622
DOI: 10.1039/C8SC04228D
CC1(C)COC(=O)N1c1nc2c(s1)CCc1cc(C#N)ccc1-2
Reaction #771432
DOI: 10.1039/C8SC04228D
CC(C)(CO)Nc1nc(-c2ccc(C#N)cc2)c(Cl)s1
Reaction #779540
DOI: 10.1039/C8SC04228D
N#Cc1ccc(-c2csc(N)n2)cc1
Reaction #824349
desired product
DOI: 10.6084/m9.figshare.5104873.v1
NCc1ccc(-c2csc(NC(=O)C3CCCN3C(=O)OCc3ccccc3)n2)cc1
Reaction #824393
2-[4-(4-Aminomethyl-phenyl)-thiazol-2-ylcarbamoyl]-pyrrolidine-1-carboxylic acid benzyl ester
DOI: 10.6084/m9.figshare.5104873.v1
CC1(C)CCC(=O)N1c1nc(-c2ccc(C#N)cc2)cs1
Reaction #887432
DOI: 10.1039/C8SC04228D
COC(=O)[C@H](Cc1ccc(O)cc1)Nc1nc(-c2ccc(C#N)cc2)cs1
Reaction #1057270
Methyl (2S)-2-{[4-(4-cyanophenyl)-1,3-thiazol-2-yl]amino}-3-(4-hydroxyphenyl)propionate
Ausbeute 53.0%DOI: 10.6084/m9.figshare.5104873.v1
Br.Br.N#Cc1ccc(-c2csc(NC3CCN(Cc4ccccc4)CC3)n2)cc1
Reaction #1062165
4-{2-[N-(1-Benzylpiperid-4-yl)amino]-1,3-thiazol-4-yl}benzonitrile dihydrobromide
Ausbeute 86.0%DOI: 10.6084/m9.figshare.5104873.v1
CN(c1nc(-c2ccc(C#N)cc2)cs1)C1CCN(Cc2ccccc2)CC1
Reaction #1062166
4-{2-[N-(1-Benzylpiperid-4-yl)-N-methylamino]-1,3-thiazol-4-yl}benzonitrile
Ausbeute 67.0%DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)CCN(c1nc(-c2ccc(C#N)cc2)cs1)C1CCN(Cc2ccccc2)CC1.O=C(O)C(=O)O
Reaction #1062167
Ethyl 3-{N-(1-benzylpiperid-4-yl)-N-[4-(4-cyano-phenyl)-1,3-thiazol-2-yl]amino}propionate oxalate
Ausbeute 84.0%DOI: 10.6084/m9.figshare.5104873.v1
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