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799597

C=C(C)c1cc(C(=O)N2Cc3ccc(N4CCC(N5CCN(C)CC5)CC4)cc3C2)c(OCc2ccccc2)cc1OCc1ccccc1
Reaction #69720
(2,4-bis-benzyloxy-5-isopropenyl-phenyl)-{5-[4-(4-methyl-piperazin-1-yl)-piperidin-1-yl]-1,3-dihydro-isoindol-2-yl}-methanone
Ausbeute 44.4%DOI: 10.6084/m9.figshare.5104873.v1
O=C1c2ccccc2CN1CC1(N2CCN(C3CC3)CC2)CCNCC1
Reaction #74278
desired product
Ausbeute 60.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(=O)NCC1(N2CCN(c3ccncc3)CC2)CCN(Cc2ccccc2)CC1
Reaction #74282
N-((1-Benzyl-4-(4-(pyridin-4-yl)piperazin-1-yl)piperidin-4-yl)methyl)acetamide
Ausbeute 52.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1cc(C)c(S(=O)(=O)N(CCOCC(=O)N2CCC(CN3Cc4ccccc4C3=O)(N3CCN(C4CC4)CC3)CC2)C2CC2)c(C)c1
Reaction #74283
crude product
Ausbeute 50.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1cc(C)c(S(=O)(=O)N2c3ccccc3C[C@H]2COCC(=O)N2CCC(CNC(=O)c3ccncc3)(N3CCN(C4CC4)CC3)CC2)c(C)c1
Reaction #74286
crude product
Ausbeute 58.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(=O)NCC1(N2CCN(c3ccncc3)CC2)CCNCC1
Reaction #74287
N-((4-(4-(pyridin-4-yl)-piperazin-1-yl)piperidin-4-yl)methyl)acetamide
Ausbeute 5.0%DOI: 10.6084/m9.figshare.5104873.v1
CCOc1ncccc1C1(OC(=O)N2CCN(C3CCN(C)CC3)CC2)C(=O)Nc2cc(F)c(C#N)cc21
Reaction #85477
title compound
Ausbeute 57.0%DOI: 10.6084/m9.figshare.5104873.v1
CCOc1ncccc1C1(OC(=O)N2CCN(C3CCN(C)CC3)CC2)C(=O)N(S(=O)(=O)c2ccc(OC)cc2OC)c2cc(F)c(C#N)cc21
Reaction #85478
title compound
Ausbeute 47.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1cc(N2CCC(N3CCN(C(C)=O)CC3)CC2)ccc1N
Reaction #175407
DOI: 10.1039/C8SC04228D
CCc1ccc(CC(CC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)C(=O)N2CCC(N3CCN(C)CC3)CC2)cc1CC
Reaction #175423
DOI: 10.1039/C8SC04228D
COc1cc(N2CCC(N3CCN(CCF)CC3)CC2)ccc1[N+](=O)[O-]
Reaction #181062
DOI: 10.1039/C8SC04228D
CCOC(=O)COc1ccc(C(=O)CN2CCN(C3CCN(C(=O)OC(C)OC(C)=O)CC3)CC2=O)cc1
Reaction #184448
DOI: 10.1039/C8SC04228D
CN1CCN(c2cccc(Nc3nc4c(-c5ccc(N6CCC(N7CCN(C)CC7)CC6)cc5)cccn4n3)c2)CC1
Reaction #187046
DOI: 10.1039/C8SC04228D
CCOC1Cc2cc(Br)ccc2C1N1CCN(C2(C)CCN(C(=O)c3c(C)ncnc3C)CC2)CC1C
Reaction #188135
DOI: 10.1039/C8SC04228D
O=C(NC(Cc1ccc2c(c1)CCCC2)C(=O)N1CCN(C2CCNCC2)CC1)N1CCC(N2CCc3ccccc3NC2=O)CC1
Reaction #192215
DOI: 10.1039/C8SC04228D
CN1CCC(N2CCN(C(=O)C(CC(N)=O)NC(=O)c3cc4ccc(Cl)cc4s3)CC2)CC1
Reaction #194113
DOI: 10.1039/C8SC04228D
COc1cc(N2CCC(N3CCN(C)CC3)CC2)c(C)cc1Nc1ncc(C)c(-c2c[nH]c3ccccc23)n1
Reaction #194430
DOI: 10.1039/C8SC04228D
CN1C2CCC1CC(N1CCN(C(=O)C(CC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)Cc3cc(Cl)c(N)c(C(F)(F)F)c3)CC1)C2
Reaction #196832
DOI: 10.1039/C8SC04228D
COC(=O)C1=C(CCc2ccccc2C(=O)N2CCNCC2)NC(CC(=O)N2CCN(C3CC4CCC(C3)N4C)CC2)=C(C(=O)OC)C1c1c(Cl)cccc1Cl
Reaction #197631
DOI: 10.1039/C8SC04228D
CCc1ccc(CC(NC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(N3CCN(C)CC3)CC2)cc1CC
Reaction #198895
DOI: 10.1039/C8SC04228D
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