BOP-Cl

O=C(CCCCCCCBr)NOCc1ccccc1
Reaction #9178
8-bromo-octanoic acid benzyloxyamide
Ausbeute 78.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
O=C([O-])C1=C(c2ccccc2)c2ccc(OCCCc3ccccc3)cc2C1=O.[NH-]C1CCCCC1
Reaction #46175
title compound
Ausbeute 59.8%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
CC(C)N1CCC(NC(=O)c2nc3ccccc3[nH]2)CC1
Reaction #46785
1H-Benzoimidazole-2-carboxylic acid (1-isopropyl-piperidin-4-yl)-amide
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
O=C(NC1CCN(c2ccncn2)CC1)c1nc2ccccc2[nH]1
Reaction #46789
1H-Benzoimidazole-2-carboxylic acid (1-pyrimidin-4-yl-piperidin-4-yl)-amide
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
O=C(Nc1ccc(N2CCOCC2=O)cc1)c1nc2ccccc2[nH]1
Reaction #46805
1H-Benzoimidazole-2-carboxylic acid [4-(3-oxo-morpholin-4-yl)-phenyl]-amide
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
COC(=O)c1cc(C(=O)NC2CCN(C(C)C)CC2)n(Cc2cc(-c3ccc(Cl)s3)on2)n1
Reaction #61522
1-[5-(5-Chloro-thiophen-2-yl)-isoxazol-3-ylmethyl]-5-(1-isopropyl-piperidin-4-ylcarbamoyl)-1H-pyrazole-3-carboxylic acid methyl ester
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2008_09
O=C(Nc1ccc(N2CCOCC2=O)cc1)c1cc(-c2ccco2)n(Cc2cc(-c3ccc(Cl)s3)on2)n1
Reaction #61533
1-[5-(5-Chloro-thiophen-2-yl)-isoxazol-3-ylmethyl]-5-furan-2-yl-1H-pyrazole-3-carboxylic acid [4-(3-oxo-morpholin-4-yl)-phenyl]-amide
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2008_09
O=C(Nc1ccc(N2CCOCC2=O)cc1)c1cc(CO)n(Cc2cc(-c3ccc(Cl)s3)on2)n1
Reaction #61536
1-[5-(5-Chloro-thiophen-2-yl)-isoxazol-3-ylmethyl]-5-hydroxymethyl-1H-pyrazole-3-carboxylic acid [4-(3-oxo-morpholin-4-yl)-phenyl]-amide
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2008_09
COCCOCCOCc1cc(C(=O)NC2CCN(C(C)C)CC2)nn1Cc1cc(-c2ccc(Cl)s2)on1
Reaction #61539
1-[5-(5-Chloro-thiophen-2-yl)-isoxazol-3-ylmethyl]-5-[2-(2-methoxy-ethoxy)-ethoxymethyl]-1H-pyrazole-3-carboxylic acid (1-isopropyl-piperidin-4-yl)-amide
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2008_09
COCCOCCOCc1cc(C(=O)NC2CCN(C(C)C)CC2)nn1CC(=O)Nc1ccc(Cl)cn1
Reaction #61546
1-[(5-Chloro-pyridin-2-ylcarbamoyl)-methyl]-5-[2-(2-methoxy-ethoxy)-ethoxymethyl]-1H-pyrazole-3-carboxylic acid (1-isopropyl-piperidin-4-yl)-amide
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2008_09
COCCOCCOc1cc(C(=O)NC2CCN(C(C)C)CC2)n(CC(=O)Nc2ccc(Cl)cn2)n1
Reaction #61551
2-[(5-Chloro-pyridin-2-ylcarbamoyl)-methyl]-5-[2-(2-methoxy-ethoxy)-ethoxy]-2H-pyrazole-3-carboxylic acid (1-isopropyl-piperidin-4-yl)-amide
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2008_09
CO[C@H]1C[C@@H](c2n[nH]c(=O)[nH]2)C[C@@H]1O[N+](=O)[O-]
Reaction #69437
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_09
CC(C)C[C@@H]1C(=O)N[C@H](C2Cc3ccccc3C2)C(=O)N1[C@@H](C(=O)N(C)C)c1ccc(F)cc1F
Reaction #73896
(2R)-2-(2,4-difluorophenyl)-2-[(3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)-6-isobutyl-2,5-dioxopiperazin-1-yl]-N,N-dimethylethanamide
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_09
—
Reaction #158209
desired product
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
O=C(O)[C@H]1CCCN(CC(O)c2ccc(-c3noc(CCC4(c5cc(Cl)cc(Cl)c5)CCCCC4)n3)cc2)C1
Reaction #158454
(3S)-1-(2-(4-(5-(2-(1-(3,5-dichlorophenyl)cyclohexyl)ethyl)-1,2,4-oxadiazol-3-yl)phenyl)-2-hydroxyethyl)-3-piperidinecarboxylic acid
Ausbeute 76.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
CC(C)(C)OC(=O)N1CC(O)(c2ccc(-c3noc(CCC4(c5cc(Cl)cc(Cl)c5)CCCCC4)n3)cc2)C1
Reaction #158455
tert-butyl 3-(4-(5-(2-(1-(3,5-dichlorophenyl)cyclohexyl)ethyl)-1,2,4-oxadiazol-3-yl)phenyl)-3-hydroxyazetidine-1-carboxylate
Ausbeute 75.2%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
O=C(Nc1c[nH]c2ncc(Br)c(F)c12)c1cccnc1
Reaction #166796
N-(5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)nicotinamide
Ausbeute 55.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
COc1ccccc1-c1n[nH]c2ncc(-c3cc(C)c(N)c(C(=O)N4CCN(CCN(C)C)CC4)c3)cc12
Reaction #175360
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
COCCCOc1cc(C(=O)N(CC2CN(C(=O)OC(C)(C)C)CC2C(C)(C)O[SiH2]C(C)(C)C)C(C)C)ccc1OC
Reaction #179257
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
Cc1ccccc1C1CCN(CC2CN(C(=O)c3ccccc3)CC2c2ccccc2)CC1
Reaction #183291
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
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