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110400

CSc1nc(Oc2cccc(C(F)(F)F)c2)cc(C(F)(F)F)n1
Reaction #898
2-methylthio-4-trifluoromethyl-6-[3-(trifluoromethyl)phenoxy]pyrimidine
DOI: 10.6084/m9.figshare.5104873.v1
CSc1ccc(-c2cc(C(F)(F)F)nc(SC)n2)cc1
Reaction #6791
title compound
Ausbeute 84.0%DOI: 10.6084/m9.figshare.5104873.v1
Clc1nc2c(c(Nc3cc(C4CC4)n[nH]3)n1)CCCC2
Reaction #7703
(2-chloro-5,6,7,8-tetrahydroquinazolin-4-yl)-(5-cyclopropyl-2H-pyrazol-3-yl)-amine
DOI: 10.6084/m9.figshare.5104873.v1
O=C(O)CCc1cc(Cl)nc(Cl)n1
Reaction #51472
3-(2,4-dichloropyrimidin-6-yl)propionic acid
Ausbeute 49.8%DOI: 10.6084/m9.figshare.5104873.v1
Nc1nc(Cl)cc(-c2cc(Cl)ccc2OCC(F)(F)F)n1
Reaction #56885
4-chloro-6-[5-chloro-2-(2,2,2-trifluoro-ethoxy)-phenyl]-pyrimidin-2-ylamine
DOI: 10.6084/m9.figshare.5104873.v1
Nc1nc(Nc2ccc(Br)cc2)cc(-c2cc(Br)ccc2OCC(F)(F)F)n1
Reaction #56888
title compound
Ausbeute 34.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #56896
hydrochloride salt
Ausbeute 63.0%DOI: 10.6084/m9.figshare.5104873.v1
Nc1nc(Cl)cc(-c2cc(Br)ccc2OCCN2CCOCC2)n1
Reaction #56919
4-[5-bromo-2-(2-morpholin-4-yl-ethoxy)-phenyl)-6-chloro-pyrimidin-2-ylamine
Ausbeute 41.0%DOI: 10.6084/m9.figshare.5104873.v1
Nc1nc(Nc2ccc(Cl)cc2)cc(-c2cc(Br)ccc2OCCN2CCOCC2)n1
Reaction #56920
title compound
Ausbeute 83.0%DOI: 10.6084/m9.figshare.5104873.v1
CSc1nc(N2CC[C@H](S(=O)(=O)c3ccccc3C(F)(F)F)C2)cc(C(F)(F)F)n1
Reaction #66322
2-Methylsulfanyl-4-trifluoromethyl-6-[(S)-3-(2-trifluoromethyl-benzenesulfonyl)-pyrrolidin-1-yl]-pyrimidine
DOI: 10.6084/m9.figshare.5104873.v1
O=C(c1cc(Cl)ncn1)N1CCc2cc(F)ccc21
Reaction #161785
(6-chloro-pyrimidin-4-yl)-(5-fluoro-2,3-dihydro-indol-1-yl)-methanone
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)CCN(C1CCN(c3cc(C(=O)n4ccc5nc(OCc6ccccc6)ccc54)ncn3)CC1)C(=O)N2
Reaction #161795
3-{1-[6-(5-benzyloxy-pyrrolo[3,2-b]pyridine-1-carbonyl)-pyrimidin-4-yl]-piperidin-4-yl}-7-methoxy-1,3,4,5-tetrahydro-benzo[d][1,3]diazepin-2-one
DOI: 10.6084/m9.figshare.5104873.v1
O=C(c1cc(N2CCC(n3c(=O)[nH]c4ncccc43)CC2)ncn1)n1ccc2ccccc21
Reaction #161828
1-{1-[6-(indole-1-carbonyl)-pyrimidin-4-yl]-piperidin-4-yl}-1,3-dihydro-imidazo[4,5-b]pyridin-2-one
DOI: 10.6084/m9.figshare.5104873.v1
O=C(c1cc(N2CCC(n3c(=O)[nH]c4ncccc43)CC2)ncn1)n1ccc2cc(F)ccc21
Reaction #161830
1-{1-[6-(5-fluoroindole-1-carbonyl)-pyrimidin-4-yl]-piperidin-4-yl}-1,3-dihydro-imidazo[4,5-b]pyridin-2-one
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2[nH]c(=O)c(C3CCN(c4cc(C(=O)N5CCc6cc(F)ccc65)ncn4)CC3)cc2c1
Reaction #161865
3-{1-[6-(5-fluoro-2,3-dihydro-indole-1-carbonyl)-pyrimidin-4-yl]-piperidin-4-yl}-6-methoxy-1H-quinolin-2-one
DOI: 10.6084/m9.figshare.5104873.v1
O=C(c1cc(N2CCC(N3Cc4cnccc4NC3=O)CC2)ncn1)N1CCc2cc(F)ccc21
Reaction #161867
3-{1-[6-(5-fluoro-2,3-dihydro-indole-1-carbonyl)-pyrimidin-4-yl]-piperidin-4-yl}-3,4-dihydro-1H-pyrido[4,3-d]pyrimidin-2-one
DOI: 10.6084/m9.figshare.5104873.v1
O=C(c1cc(N2CCC(N3Cc4cccnc4NC3=O)CC2)ncn1)N1CCc2cc(F)ccc21
Reaction #161870
3-{1-[6-(5-fluoro-2,3-dihydro-indole-1-carbonyl)-pyrimidin-4-yl]-piperidin-4-yl}-3,4-dihydro-1H-pyrido[2,3-d]pyrimidin-2-one
DOI: 10.6084/m9.figshare.5104873.v1
Clc1cc(-c2ccccc2)nc(Cl)n1
Reaction #162589
2,4-dichloro-6-phenylpyrimidine
DOI: 10.6084/m9.figshare.5104873.v1
Clc1cc(-c2ccccc2)nc(Cl)n1
Reaction #162616
2,4-dichloro-6-phenylpyrimidine
Ausbeute 110.1%DOI: 10.6084/m9.figshare.5104873.v1
Cc1ccc(C(C)C)cc1N1CCc2nc(-c3c(C)ccc4[nH]nc(C)c34)nc(Cl)c2C1
Reaction #168033
4-chloro-2-(3,5-dimethyl-1H-indazol-4-yl)-6-(5-isopropyl-2-methylphenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
DOI: 10.6084/m9.figshare.5104873.v1
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