بحث البنية الفرعية

799034

CC(C)N1CCN(c2ccc(Nc3cc(Cl)nn4ccnc34)nc2)CC1
Reaction #490112
(6-chloro-imidazo[1,2-b]pyridazin-8-yl)-[5-(4-isopropyl-piperazin-1-yl)-pyridin-2-yl]-amine
المردود 24.3%DOI: 10.6084/m9.figshare.5104873.v1
CN1CCN(c2ccc(Nc3cc(Cl)nn4ccnc34)nc2)CC1
Reaction #1111205
104b
المردود 101.8%DOI: 10.6084/m9.figshare.5104873.v1
CN1CCN(c2ccc(Nc3cc(-c4cc(F)cc(N5CCn6c(cc7c6CCCC7)C5=O)c4CO)nn4ccnc34)nc2)CC1
Reaction #1111206
104
المردود 20.1%DOI: 10.6084/m9.figshare.5104873.v1
Clc1cc(Nc2ccc(N3CCN(C4COC4)CC3)cn2)c2nccn2n1
Reaction #1111207
105a
المردود 77.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C1c2cc3c(n2CCN1c1cc(F)cc(-c2cc(Nc4ccc(N5CCN(C6COC6)CC5)cn4)c4nccn4n2)c1CO)CCCC3
Reaction #1111208
105
المردود 9.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C1c2sc3c(c2CCN1c1cc(F)cc(-c2cc(Nc4ccc(N5CCN(C6COC6)CC5)cn4)c4nccn4n2)c1CO)CCCC3
Reaction #1111234
111
المردود 22.0%DOI: 10.6084/m9.figshare.5104873.v1
O=c1c2sc3c(c2cnn1-c1cc(F)cc(-c2cc(Nc4ccc(N5CCN(C6COC6)CC5)cn4)c4nccn4n2)c1CO)CCCC3
Reaction #1111235
112
المردود 12.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C1c2cc3c(n2CCN1c1nccc(-c2cc(Nc4ccc(N5CCN(C6COC6)CC5)cn4)c4nccn4n2)c1CO)CCCC3
Reaction #1111245
114
المردود 4.0%DOI: 10.6084/m9.figshare.5104873.v1
C[C@H]1CN(C(=O)OC(C)(C)C)CCN1c1ccc(Nc2cc(Cl)nn3ccnc23)nc1
Reaction #1111248
115c
المردود 80.0%DOI: 10.6084/m9.figshare.5104873.v1
Br.C[C@H]1CNCCN1c1ccc(Nc2cc(Br)nn3ccnc23)nc1
Reaction #1111249
115d
المردود 65.0%DOI: 10.6084/m9.figshare.5104873.v1