بحث البنية الفرعية

253772

CC(C)c1ccc2c(Nc3cc(C(=O)Nc4ccc(-c5c[nH]c([C@@H]6CCCN6C(=O)Cc6ccccc6)n5)cc4)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1
Reaction #72727
solid
المردود 36.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)c1ccc2c(Nc3cc(C(=O)Nc4ccc(-c5c[nH]c([C@@H]6CCCN6C(=O)[C@@H](c6ccccc6)N(C)C)n5)cc4)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1
Reaction #72729
solid
المردود 55.4%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)c1ccc2c(Nc3cc(C(=O)Nc4ccc(NC(=O)[C@@H]5CCCN5C(=O)OCc5ccccc5)cc4)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1
Reaction #72732
solid
المردود 64.9%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)c1ccc2c(Nc3cc(C(=O)NC(C)c4ccccc4)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1
Reaction #177001
DOI: 10.1039/C8SC04228D
CC(C)c1nc2ncnc(Nc3cc(C(=O)O)ccc3Sc3ccc(N)cc3)c2cc1F
Reaction #208942
DOI: 10.1039/C8SC04228D
CC(C)c1ccc2c(Nc3cc(C(=O)NCc4cccs4)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1
Reaction #238099
DOI: 10.1039/C8SC04228D
CC(C)c1ccc2c(Nc3cc(C(=O)NC(C)(COP(=O)(OC(C)(C)C)OC(C)(C)C)c4ccccc4)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1
Reaction #261731
DOI: 10.1039/C8SC04228D
CC(C)c1ccc2c(Nc3cc(C(=O)NC(C)(C)COP(=O)(OC(C)(C)C)OC(C)(C)C)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1
Reaction #262812
DOI: 10.1039/C8SC04228D
CC(C)c1ccc2c(Nc3cc(C(=O)NCc4ccccc4Br)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1
Reaction #265504
DOI: 10.1039/C8SC04228D
Cc1cccc(CCNC(=O)c2ccc(Sc3ccc(NC(=O)OC(C)(C)C)cc3)c(Nc3ncnc4nc(C(C)C)ccc34)c2)c1
Reaction #265644
DOI: 10.1039/C8SC04228D
CC(C)c1ccc2c(Nc3cc(C(=O)NCc4ccccc4)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1
Reaction #290213
DOI: 10.1039/C8SC04228D
CC(C)(C)OC(=O)Nc1ccc(Sc2ccc(C(=O)O)cc2Nc2ncnc3nc(C(C)(C)C)ccc23)cc1
Reaction #299753
DOI: 10.1039/C8SC04228D
CC(C)c1ccc2c(Nc3cc(C(=O)N(C)C(C)c4ccccc4)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1
Reaction #385598
DOI: 10.1039/C8SC04228D
CC(C)c1ccc2c(Nc3cc(C(=O)NC(C)c4ccncc4)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1
Reaction #387202
DOI: 10.1039/C8SC04228D
CC(C)c1ccc2c(Nc3cc(C(=O)O)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1
Reaction #388034
DOI: 10.1039/C8SC04228D
CCOC(=O)C(C)(NC(=O)c1ccc(Sc2ccc(NC(=O)OC(C)(C)C)cc2)c(Nc2ncnc3nc(C(C)C)ccc23)c1)c1ccccc1
Reaction #395288
DOI: 10.1039/C8SC04228D
Cc1ccccc1CNC(=O)c1ccc(Sc2ccc(NC(=O)OC(C)(C)C)cc2)c(Nc2ncnc3nc(C(C)C)ccc23)c1
Reaction #400469
DOI: 10.1039/C8SC04228D
Cc1ccc(CNC(=O)c2ccc(Sc3ccc(NC(=O)OC(C)(C)C)cc3)c(Nc3ncnc4nc(C(C)C)ccc34)c2)cc1
Reaction #408418
DOI: 10.1039/C8SC04228D
—
Reaction #692514
crystal
المردود 65.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)c1ccc2c(Nc3cc(C(=O)O)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1
Reaction #692515
title compound
المردود 98.0%DOI: 10.6084/m9.figshare.5104873.v1
الصفحة 1التالي