تفاعل #72729

معادلة التفاعل

Product

(R)-1-((S)-2-(4-(4-aminophenyl)-1H-imidazol-2-yl)pyrrolidin-1-yl)-2-(dimethylamino)-2-phenylethanone

product

4-(4-tert-Butoxycarbonylamino-phenylsulfanyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-benzoic acid

→

solid

المردود 55.4%

tert-butyl 4-(4-(4-(2-((S)-1-((R)-2-(dimethylamino)-2-phenylacetyl)pyrrolidin-2-yl)-1H-imidazol-4-yl)phenylcarbamoyl)-2-(7-isopropylpyrido[2,3-d]pyrimidin-4-ylamino)phenylthio)phenylcarbamate

المردود 55.4%

ظروف التفاعل

الإجراء التجريبي

A solution of the Product of Example 2C (0.081 g, 0.21 mmol) and the product from Example 1E (0.10 g, 0.188 mmol) was processed in the same manner as in Example 1K to give a solid (0.094 g, 55%).

المصدر