反应 #992700

反应方程式

3-methyl-N-(1-methylethyl)-2-nitrobenzeneacetamide

title product

3-methyl-N-(1-methylethyl)-2-nitrobenzeneacetamide

→

title compound

2-amino-3-methyl-N-(1-methylethyl)benzeneacetamide

溶剂

ethanol

反应条件

后处理

1. 1
   其他was placed under a balloon of nitrogen overnight
2. 2
   过滤Then the reaction mixture was filtered through Celite® diatomaceous filter aid
3. 3
   其他The solvent was removed with a rotary evaporator

实验过程

To 3-methyl-N-(1-methylethyl)-2-nitrobenzeneacetamide (i.e. the title product of Step A) (0.40 g, 1.7 mmol) and 10% palladium on carbon (0.13 g) was added 20 mL of ethanol. The reaction mixture was placed under a balloon of nitrogen overnight. Then the reaction mixture was filtered through Celite® diatomaceous filter aid. The solvent was removed with a rotary evaporator to afford the title compound as a tan solid (0.29 g).

来源