反应 #9815

反应方程式

6-Nitro-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide

hydrogen

→

title compound

收率 46.4%

6-Amino-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide

收率 46.4%

溶剂

THF

MeOH

反应条件

后处理

1. 1
   过滤The catalyst was filtered off
2. 2
   其他the filtrate evaporated
3. 3
   其他the residue chromatographed on silica

实验过程

0.917 g 6-Nitro-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide (from g)) were hydrogenated in a mixture of 20 ml THF and 20 ml MeOH with 0.90 g 5% Pd—C at atmospheric hydrogen pressure for 90 min. at room temperature. The catalyst was filtered off, the filtrate evaporated and the residue chromatographed on silica to yield 370 mg of the title compound.

来源