反应 #969874

反应方程式

( D )

Z-Val-Pro-Val-Pro Ara-C

→

H-Val-Pro-Val-Pro Ara-C

收率 90.0%

溶剂

methanol

反应条件

后处理

1. 1
   过滤The reaction mixture was filtered
2. 2
   其他the filtrate was evaporated to dryness, under reduced pressure
3. 3
   其他to give D (90% yield)

实验过程

A solution of the corresponding Ara-C-tetrapeptide-Z-protected (D) (24.7 mg, 0.03 mmol) in methanol containing Pd/C (10% wt/wt) (11.5 mg) was hydrogenated at 25 psi at room temperature for 2 h. The reaction mixture was filtered, and the filtrate was evaporated to dryness, under reduced pressure, to give D (90% yield).

来源