反应 #955949

反应方程式

9-(Bromomethyl)phenanthrene

triethyl phosphite

→

product

收率 56.8%

diethyl (phenanthren-9-ylmethyl)phosphonate

收率 56.8%

反应条件

后处理

1. 1
   浓缩The reaction mixture was concentrated
2. 2
   其他the residue was purified by silica gel column chromatography

实验过程

9-(Bromomethyl)phenanthrene (18 g, 66.4 mmol) and triethyl phosphite (10.7 g) were mixed and heated to 150° C. under N2 for 4 h. The reaction mixture was concentrated and the residue was purified by silica gel column chromatography to yield 12 g of product.

来源