反应 #955919

反应方程式

5-(2,4-dimethoxybenzyl)-2H-1,2,4-triazole-3(4H)-thione

2-(bromomethyl)pyridine hydrobromide

→

2-((5-(2,4-dimethoxybenzyl)-1H-1,2,4-triazol-3-ylthio)methyl)pyridine

收率 34.0%

反应条件

实验过程

Prepared in a similar manner to example 1 using 5-(2,4-dimethoxybenzyl)-2H-1,2,4-triazole-3(4H)-thione (example 9a) and 2-(bromomethyl)pyridine hydrobromide. Yield 34%. 1H NMR (500 MHz, CDCl3): δ 3.77 (s, 3H), 3.79 (s, 3H), 4.0 (s, 2H), 4.34 (s,2H), 6.35-6.45 (m, 2H), 7.1 (d, 1H), 7.15 (t, 1H), 7.3 (d, 1H), 7.7 (t, 1H), 8.5 (s, 1H). MS(M+H, 343).

来源