反应 #95250

反应方程式

2-(5-carboxypentyl)-2-cyclopentenone

p-toluenesulfonic acid

→

2-(5-carbethoxypentyl)-2-cyclopentenone

溶剂

ethanol

反应条件

后处理

1. 1
   其他The solvent is evaporated
2. 2
   workup.DISSOLUTIONthe residue is dissolved in ether
3. 3
   洗涤The organic phase is washed with water, sodium bicarbonate solution, and saturated saline solution
4. 4
   干燥dried (MgSO4)
5. 5
   其他evaporated
6. 6
   其他to give 1.371 g

实验过程

A solution of 1.309 g. (0.00668 mole) of 2-(5-carboxypentyl)-2-cyclopentenone (Example 52) and 90 mg. of p-toluenesulfonic acid in 150 ml. of ethanol is refluxed for 18 hours. The solvent is evaporated and the residue is dissolved in ether. The organic phase is washed with water, sodium bicarbonate solution, and saturated saline solution, dried (MgSO4), and evaporated to give 1.371 g. of a light yellow oil.

来源