反应 #95064

反应方程式

N-(3-oxocyclohexyl)acetamide

3-methoxyphenylhydrazine hydrochloride

H2O

→

title compound

N-(1,3,4,9-tetrahydro-7-methoxy-2H-carbazol-2-yl)acetamide

溶剂

HOAc

反应条件

后处理

1. 1
   温度refluxed for 2 hr
2. 2
   其他The cooled reaction mixture
3. 3
   其他the product triturated until solid
4. 4
   过滤Filtration
5. 5
   其他drying
6. 6
   其他recrystallization from ethanol

实验过程

A mixture of 0.05 mol of N-(3-oxocyclohexyl)acetamide and 0.05 mol of 3-methoxyphenylhydrazine hydrochloride in 50 ml of glacial HOAc was stirred for 2 hr at room temperature and then refluxed for 2 hr. The cooled reaction mixture was poured into H2O and the product triturated until solid. Filtration, drying, and recrystallization from ethanol gave the title compound, mp 192°-193°.

来源