反应 #9506

反应方程式

4-Chloro-3-nitro-7-phenylquinoline

1-(3-aminopropyl)pyrrolidin-2-one

→

1-[3-(3-nitro-7-phenylquinolin-4-ylamino)propyl]pyrrolidin-2-one

收率 88.1%

反应条件

实验过程

4-Chloro-3-nitro-7-phenylquinoline (3.51 g, 12.3 mmol) was treated with 1-(3-aminopropyl)pyrrolidin-2-one (2.3 mL, 16 mmol) according to the method described in Part E of Example 1 to provide 4.23 g of 1-[3-(3-nitro-7-phenylquinolin-4-ylamino)propyl]pyrrolidin-2-one as a yellow solid.

来源