反应 #94547

反应方程式

Tri-n-butyl phosphine

monochloroacetic acid

phosphine

→

Tri-n-butyl(carboxymethyl)phosphonium Chloride

溶剂

methanol

反应条件

后处理

1. 1
   其他did not exceed about 30° C
2. 2
   其他The methanol solvent was subsequently evaporated under reduced pressure
3. 3
   其他leaving a colorless viscous liquid whose infrared spectrum and elemental analysis

实验过程

Tri-n-butyl phosphine (4.04 g, 0.02 mole) was added dropwise to a rapidly stirred solution of monochloroacetic acid (1.85 g, 0.02 mole) and 3.2 ml of methanol. The addition of the phosphine was at a rate such that the reaction temperature did not exceed about 30° C. The methanol solvent was subsequently evaporated under reduced pressure leaving a colorless viscous liquid whose infrared spectrum and elemental analysis corresponded to a compound of the formula

来源