反应 #939019

反应方程式

6-decenoic acid

Methyl 6-bromodecanoate

quinoline

methyl 5-decenoate

methyl 6-decenoate

→

5-decenoic acid

收率 35.0%

反应条件

后处理

1. 1
   其他to react at 240° C. for 5 minutes
2. 2
   萃取the reaction solution was extracted with ether
3. 3
   洗涤washed with dilute sulfuric acid
4. 4
   洗涤washed with water
5. 5
   其他dried
6. 6
   其他evaporated
7. 7
   其他to remove the solvent
8. 8
   workup.DISTILLATIONdistilled
9. 9
   其他giving

实验过程

Methyl 6-bromodecanoate (1.2 g) and quinoline (1.2g) were mixed together, and then allowed to react at 240° C. for 5 minutes. After the reaction was completed, the reaction solution was extracted with ether, washed with dilute sulfuric acid, washed with water, dried, evaporated to remove the solvent, and then distilled, thereby giving a mixture of methyl 5-decenoate and methyl 6-decenoate (310 mg). The mixture was hydrolyzed in a coventional manner, thereby giving a mixture (270 mg) of 5-decenoic acid and 6-decenoic acid (1/1).

来源