反应 #935825

反应方程式

1-chloro-3,4-dimethyl-2,6-dinitrobenzene

di-n-propylamine

→

3,4-Dimethyl-2,6-dinitro-N,N-di-n-propylaniline

溶剂

benzene

反应条件

后处理

1. 1
   温度the mixture is refluxed
2. 2
   其他The benzene is then removed from the mixture
3. 3
   workup.ADDITIONtoluene is added to the remaining residue
4. 4
   温度The thus-formed mixture is then refluxed
5. 5
   过滤filtered
6. 6
   workup.ADDITIONThe residue is treated with hexane
7. 7
   温度the mixture chilled in dry ice
8. 8
   其他The solid from the mixture is collected
9. 9
   其他dried

实验过程

Five grams of 1-chloro-3,4-dimethyl-2,6-dinitrobenzene and 5.05 grams of di-n-propylamine are dissolved in benzene and the mixture is refluxed. The benzene is then removed from the mixture by boiling and toluene is added to the remaining residue. The thus-formed mixture is then refluxed, filtered, and the filtrate stripped in vacuo. The residue is treated with hexane and the mixture chilled in dry ice and acetone. The solid from the mixture is collected and dried, it has a melting point of 42° C. to 43.5° C. and is the desired product.

来源