反应 #92934

反应方程式

1-phenyl-1-oxo-2-bromopropane

1-methylimidazole

→

1-methyl-3-(1-methyl-2-phenyl-2-oxoethyl)-1H-imidazolium bromide

收率 55.0%

溶剂

diethyl ether

反应条件

后处理

1. 1
   过滤The precipitated solid was collected by filtration
2. 2
   洗涤washed with diethyl ether
3. 3
   workup.DISSOLUTIONdissolved in methanol
4. 4
   workup.ADDITIONThis solution was diluted with diethyl ether
5. 5
   过滤the resulting white solid was collected by filtration
6. 6
   其他This solid was recrystallized from methanol/diethyl ether

实验过程

A solution of 8 ml (0.047 mol) of 90% pure 1-phenyl-1-oxo-2-bromopropane and 4.25 g (0.052 mol) of 1-methylimidazole in 100 ml of diethyl ether was stirred at room temperature for approximately 24 hours. The precipitated solid was collected by filtration, washed with diethyl ether and dissolved in methanol. This solution was diluted with diethyl ether and the resulting white solid was collected by filtration. This solid was recrystallized from methanol/diethyl ether to afford 7.65 g of 1-methyl-3-(1-methyl-2-phenyl-2-oxoethyl)-1H-imidazolium bromide as white crystals. (55% yield) mp=167°-170° C.

来源