反应 #92932

反应方程式

1-bromo-2-(4-ethylphenyl)-2-oxoethane

1-methylimidazole

→

1-methyl-3-[2-(4-ethylphenyl)-2-oxoethyl]-1H-imidazolium bromide

收率 38.2%

溶剂

diethyl ether

反应条件

后处理

1. 1
   其他The reaction solvent was decanted
2. 2
   洗涤the residue was washed with diethyl ether
3. 3
   workup.DISSOLUTIONdissolved in a small amount of acetonitrile
4. 4
   workup.ADDITIONThe resulting solution was diluted with a small amount of ethyl acetate, whereupon a brown precipitate
5. 5
   其他formed
6. 6
   其他The solid was collected
7. 7
   其他recrystallized from acetonitrile/ethyl acetate

实验过程

A solution of 4.41 g (0.019 mol) of 1-bromo-2-(4-ethylphenyl)-2-oxoethane and 1.65 g (0.02 mol) of 1-methylimidazole in 40 ml of diethyl ether was stirred at room temperature for approximately 18 hours. The reaction solvent was decanted, and the residue was washed with diethyl ether and dissolved in a small amount of acetonitrile. The resulting solution was diluted with a small amount of ethyl acetate, whereupon a brown precipitate formed. The solid was collected and recrystallized from acetonitrile/ethyl acetate to provide 2.26 g of 1-methyl-3-[2-(4-ethylphenyl)-2-oxoethyl]-1H-imidazolium bromide as fine yellow brown needles. (38% yield) mp=177°-179° C.

来源