反应 #927254

反应方程式

1-(7-hydroxyheptyl)-cyclopropene

Triethylamine

methanesulfonyl chloride

→

1-(7-methanesulfonyloxyheptyl)-cyclopropene

溶剂

ether

反应条件

后处理

1. 1
   洗涤The reaction mixture was washed with water and brine
2. 2
   干燥dried over magnesium sulfate
3. 3
   过滤filtered

实验过程

A solution of 3.8 mmol of 1-(7-hydroxyheptyl)-cyclopropene in 50 ml of ether was cooled in an ice bath. Triethylamine (1 ml) and 0.48 g of methanesulfonyl chloride (4.2 mmol) were added and the reaction mixture was stirred for 2½ hours at 0° C. The reaction mixture was washed with water and brine, dried over magnesium sulfate, filtered and stripped to give 1-(7-methanesulfonyloxyheptyl)-cyclopropene which was used without further purification.

来源