反应 #927225

反应方程式

water

triethylamine

para-acetylaminophenol

lauroyl chloride

→

Lauroyl [4-(N-acetylamino)]phenol

收率 12.0%

溶剂

DMF

反应条件

后处理

1. 1
   其他the product precipitates
2. 2
   洗涤It is washed with heptane
3. 3
   其他dried under vacuum

实验过程

An equivalent amount in moles of para-acetylaminophenol and lauroyl chloride are placed in contact at 0° C. in DMF (dilution=15%) in the presence of one molar equivalent of triethylamine. The mixture is allowed to warm to room temperature with stirring and the reaction medium is then poured into water and the product precipitates. It is washed with heptane and then dried under vacuum. The yield is 12%. The elemental analysis is in accordance with the structure.

来源