反应 #89988

ord-3a4c6b8ecdf849daa488f6ef8db126ce

反应方程式

CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
Compound A6
CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
8-Hydroxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
CCOC(=O)NCCCl
ethyl-2-chloroethylcarbamate
→
CCOC(=O)NCCOc1ccc2c(c1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O
title compound
CCOC(=O)NCCOc1ccc2c(c1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O
[2-(3-Cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yloxy)-ethyl]-carbamic acid ethyl ester

反应物

CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
Compound A6
CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
8-Hydroxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
CCOC(=O)NCCCl
ethyl-2-chloroethylcarbamate

试剂

无

反应条件

详细条件
See reaction.notes.procedure_details.

后处理

  1. 1
    其他Under the same conditions as the method for synthesizing Compound A7-17

实验过程

Under the same conditions as the method for synthesizing Compound A7-17, the title compound was prepared from Compound A6 and ethyl-2-chloroethylcarbamate.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US09440922B2uspto-grants-2016_09