反应 #8783

ord-4ad9440d1efb4de2a501b320e0a53821

反应方程式

BrCCCOc1cccc(-c2noc3ccsc23)c1
3-[3-(3-bromo-propoxy)-phenyl]-thieno[2,3-d]isoxazole
O=C([O-])[O-].[K+].[K+]
potassium carbonate
COc1cccc(CN)c1
3-methoxybenzylamine
COc1cccc(CNCCCOc2cccc(-c3noc4ccsc34)c2)c1
title compound
COc1cccc(CNCCCOc2cccc(-c3noc4ccsc34)c2)c1
(3-methoxy-benzyl)-[3-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-propyl]-amine

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

The title compound is prepared from 3-[3-(3-bromo-propoxy)-phenyl]-thieno[2,3-d]isoxazole, potassium carbonate, 3-methoxybenzylamine and acetonitrile essentially as described above in example 48. Purity by LC/MS (APCI)=93%, [M+H]+=395.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US07091199B1uspto-grants-2006_08