反应 #8771

反应方程式

3-[3-(2-bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole

potassium carbonate

3-methoxybenzylamine

→

title compound

(3-methoxy-benzyl)-[2-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-ethyl]-amine

溶剂

acetonitrile

反应条件

后处理

1. 1
   洗涤is eluted with a graded solvent mixture of 50% ethyl acetate in heptane to 100% ethyl acetate

实验过程

The title compound is prepared from 3-[3-(2-bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole, potassium carbonate, 3-methoxybenzylamine and acetonitrile essentially as described above in example 35, except that the column is eluted with a graded solvent mixture of 50% ethyl acetate in heptane to 100% ethyl acetate. Purity by LC/MS (APCI)=99%, [M+H]+=381.

来源