反应 #87649

反应方程式

5-((2,2,2-trifluoroacetamido)methyl)-2-chloro-4-methoxybenzamide

oxalyl chloride

→

desired product

5-((2,2,2-trifluoroacetamido)methyl)-2-chloro-4-methoxybenzoyl isocyanate

溶剂

EDC

反应条件

后处理

1. 1
   其他The title compound was prepared

实验过程

The title compound was prepared according to the procedure described in step-2 of Intermediate-8 by using 5-((2,2,2-trifluoroacetamido)methyl)-2-chloro-4-methoxybenzamide (1.0 g, 3.6 mmol), oxalyl chloride (1.0 mL) and EDC (10 mL) to afford 0.750 g of the desired product.

来源